In recent years scientific and technological advancements have been produced many classes of Antiulcer drugs in the medicinal market, such drugs are used to treat the ulcer as quick remedies in people, so we selected some drugs for our studies and market survey then to find out the fast movable antiulcer drug had a potential of some selected antiulcer drugs and the reasons for most leading sale...

Peptic ulcer disease is a deep gastrointestinal erosion disorder that involves the entire mucosal thickness and can even penetrate the muscular mucosa. Numerous natural products have been evaluated as therapeutics for the treatment of a variety of diseases, including this one. These products usually derive from plant and animal sources that contain active constituents such as alkaloids, flavono...

The antiulcer effects of different tricyclic antidepressants (trimipramine, doxepin, imipramine, and amitriptyline) in comparison with those of cimetidine, pirenzepine and omeprazole were investigated in male rats with acute gastric ulcer. Acute gastric ulcer was induced by oral administration of O. 6N HCl solution, 1 mL/rat. Pretreatment of animals with doxepin, trimipramine, amitriptylin...

OBJECTIVE Even though there are many drugs for the treatment of gastric ulcers, these drugs sometimes cannot succeed. Since the 1950s, antidepressant drugs have been used for several non-psychiatric indications. Many antidepressant drugs have been shown experimentally to produce antiulcer activity in various ulcer models. Moclobemide is an antidepressant drug which inhibits monoamine oxidase-A ...

Amino acids are safe molecules with variable efficacy against ulceration. Considering the good antioxidant potential of N-aroyl- N, N'-dicyclohexyl urea and antiulcer activities of amino acids, a series of amino acid conjugates of N-aroyl- N, N'-dicyclohexyl urea was synthesized and the effect against ulceration in albino rats induced by pyloric ligation was screened. All these compounds were f...

Ocimum sanctum is a medicinal plant which has been used studied for various properties and used in various conditions.In the present study, ocimum sanctum was investigated for its effects against swimming stress induced ulcers in albino rats. The effects were compared with ranitidine. The leaf extract of ocimum sanctum showed significant antiulcer activity in the dose of 100 mg/kg and 200 mg/kg...

Effects of FRG-8701, a new histamine H2-receptor antagonist, on gastric acid secretion, necrotizing agents-induced gastric lesions and acute gastric or duodenal ulcer in rats were studied. In lumen-perfused rats, intravenous injection of FRG-8701 reduced gastric acid secretion, and its antisecretory effect was almost equipotent to that of famotidine but the duration of action was substantially ...

BACKGROUND The roots of Zapoteca portricensis is a common remedy in the treatment gastrointestinal disorders used by tradomedical practitioners in Eastern Nigeria. AIM This study was aimed at evaluating the possible antiulcer activity of the root of this plant in experimental rats. METHODS A methanolic root extract was prepared by cold maceration. Antiulcer activity was tested using absolut...