نتایج جستجو برای: antipruritics
تعداد نتایج: 115 فیلتر نتایج به سال:
The existing evidence for treatment of atopic eczema (atopic dermatitis, AE) is evaluated using the national standard Appraisal of Guidelines Research and Evaluation. The consensus process consisted of a nominal group process and a DELPHI procedure. Management of AE must consider the individual symptomatic variability of the disease. Basic therapy is focused on hydrating topical treatment, and ...
Resorcinol, also known as resorcin (1,3-dihydroxybenzene; CAS no. 108-46-3), is an important ingredient of Castellani’s paint solution, an antifungal preparation that is commonly used in daily dermatological clinical practice. Apart from its use in hair dyes, resorcinol is also used in several other topical preparations, because of its antipruritic, keratolytic and antimycotic properties. Sodiu...
Reverse osmosis (RO) concentrate from wastewater reuse facilities contains concentrated emerging pollutants, such as pharmaceuticals. In this research, a paper-like composite sheet consisting of titanium dioxide (TiO2) and zeolite was synthesized, and removal of the antipruritic agent crotamiton from RO concentrate was studied using the TiO2/zeolite composite sheet. The RO concentrate was obtai...
Itch is frequently associated with dermatoses characterized by a defective skin barrier. We formulated an itch-relieving moisturizing cream containing 3% menthol and ceramides. Our aim was to evaluate the safety and antipruritic efficacy of application of this cream in volunteers with and without skin diseases. Volunteers were asked to apply the cream for 1 month on a minimum body surface area ...
This Review highlights selected frontiers in pruritus research and focuses on recently attained insights into the neurophysiological, neuroimmunological, and neuroendocrine mechanisms underlying skin-derived itch (pruritogenic pruritus), which may affect future antipruritic strategies. Special attention is paid to newly identified itch-specific neuronal pathways in the spinothalamic tract that ...
BACKGROUND Chronic pruritus is a global clinical problem with a high impact on the quality of life and lack of specific therapies. It is an excruciating and frequent symptom of e.g. uncurable renal, liver and skin diseases which often does not respond to conventional treatment with e.g. antihistamines. Therefore antipruritic therapies which target physiological mechanisms of pruritus need to be...
BACKGROUND & AIMS The efficacy of currently available therapeutic agents for cholestatic pruritus is often disappointing. The aim of this study was to assess the antipruritic effect of naltrexone, an oral opiate receptor antagonist. METHODS Sixteen patients with pruritus of chronic cholestasis were randomized to receive naltrexone (4-week course of 50 mg naltrexone daily) or placebo. Pruritus...
Specific dermatoses of pregnancy refer to a group of skin diseases that are encountered predominantly during or immediately following pregnancy. This is a case report of pruritic urticarial papules and plaques of pregnancy developing in a 29-year-old lady primigravida lady is associated with overt diabetes with hypothyroidism, pre-eclampsia and anemia. The diagnosis of PUPPP is a clinical one, ...
The existing evidence for treatment of atopic eczema (atopic dermatitis, AE) is evaluated using the national standard Appraisal of Guidelines Research and Evaluation. The consensus process consisted of a nominal group process and a DELPHI procedure. Management of AE must consider the individual symptomatic variability of the disease. Basic therapy is focused on hydrating topical treatment, and ...
OBJECTIVES Aristolochia indica has been widely used in the traditional medicine for the treatment of a variety of diseases. In the present study different extracts of roots of A. indica were evaluated for their anti-inflammatory, antipruritic and mast cell stabilizing activity. MATERIALS AND METHODS Anti-inflammatory activity was performed by compound 48/80 induced rat paw edema model and ant...
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