BACKGROUND Rubbing moist skin results in higher frictional forces than rubbing very dry skin. As friction increases, the probability of activity-related blisters also increases. Therefore reducing moisture may reduce blister incidence during physical activity. OBJECTIVE We examined whether an antiperspirant can reduce foot blisters during hiking. METHODS In a double-blind study, cadets atte...

No one likes to sweat, but with hot, humid summer weather, it's difficult avoid. And for patients hyperhidrosis, a medical condition that causes excessive sweating, fighting perspiration becomes an important part of daily life. Fortunately, several kinds antiperspirants are available help. FDA defines antiperspirant as “a drug product applied topically reduces the production (sweat) at site.” T...

Bai Shao (BS, the root of Paeonia lactiflora Pall.), a common Chinese herb in many recipes used to treat viral infection and liver diseases, is recognized for its ability to nourish menstruation, its Yin convergence, and as an antiperspirant. However, the mechanism and components for its antiviral function remain to be elucidated. In this study, an ethanolic extract of BS was further partitione...

A prospective analysis of risk factors for Alzheimer's disease was a major objective of the Canadian Study of Health and Aging, a nationwide, population-based study. Of 6,434 eligible subjects aged 65 years or older in 1991, 4,615 were alive in 1996 and participated in the follow-up study. All participants were cognitively normal in 1991 when they completed a risk factor questionnaire. Their co...

Use of underarm aluminium (Al)-based antiperspirant salts may be a contributory factor in breast cancer development. At the 10th Keele meeting, Al was reported to cause anchorage-independent growth and double strand DNA breaks in MCF10A immortalised non-transformed human breast epithelial cells. We now report that exposure of MCF10A cells to Al chloride or Al chlorohydrate also compromised DNA ...

As scientists seek to characterize human exposures to chemicals, they need more valid, accurate biomarkers—telltale molecular signatures that indicate a particular exposure has occurred. A team from the CDC has now provided the field with a new biomarker that could help researchers document exposures to a class of antimicrobial preservatives called parabens [EHP 114:1843–1846; Ye et al.]. Parab...

The socket of a prosthesis is a tightly closed container. Sweating inside the socket is annoying and may also irritate the skin over the stump or lead to local infection such as folliculitis. The most effective method of preventing sweating is by the use of astringent agents. Formaldehyde is a very strong astringent but is not pleasant to use and may cause skin irritation and systemic reactions...

Title: Aluminum concentrations in central and peripheral areas of malignant breast lesions do not differ from those in normal breast tissues Thank you very much for the diligent review of our manuscript, which we are pleased to resubmit in its revised form. We addressed each of the referees' concerns carefully, and responded to their queries and demands in a point-by-point response letter. In t...

BACKGROUND Elevated concentrations of doxorubicin are found in eccrine sweat glands of the palms and soles. We therefore evaluated an antiperspirant as preventive treatment for palmar-plantar erythrodysesthesia (hand-foot syndrome) in patients with metastatic breast cancer treated with pegylated liposomal doxorubicin. PATIENTS AND METHODS An antiperspirant containing aluminum chlorohydrate or...

BACKGROUND Human axillary odour is commonly attributed to the bacterial degradation of precursors in sweat secretions. To assess the role of bacterial communities in the formation of body odours, we used a culture-independent approach to study axillary skin microbiota and correlated these data with olfactory analysis. RESULTS Twenty-four Caucasian male and female volunteers and four assessors...