Antihistamines are H1-receptor antagonists widely used in human and veterinary medicine to provide symptomatic relief of allergic signs caused by histamine release, including pruritus and anaphylactic reactions. Antihistamines are also commonly used as sedatives and antiemetics. 1 Antihistamines can be divided into first and second-generation (also called nonsedating) agents (Table 1). First-ge...

BACKGROUND Acute cough due to upper respiratory tract infection (URTI) is a common symptom. Non-prescription over-the-counter (OTC) medicines are frequently recommended as a first-line treatment, but there is little evidence as to whether these drugs are effective. OBJECTIVES To assess the effects of oral OTC cough preparations for acute cough. SEARCH STRATEGY We searched the Cochrane Centr...

A case of toxic psychosis due to antihistamine poisoning is described. The reversal of this state by physostigmine supports the contention that it is caused by an anticholinergic syndrome. The management of antihistamine poisoning is discussed.

Antihistamine-induced hepatitis is rare. We present 2 cases of antihistamine-induced hepatitis with autoimmune features, caused by loratidine. One case was confirmed by rechallenge. Identifying and discontinuing the offending agent are essential for treatment.

Background: Acne vulgaris is a common skin disease that affects not only teenagers but also the general population. Although acne is not physically disabling, its psychological impact can be striking, contributing to low self-esteem, depression, and anxiety. As a result, there is a significant demand for effective acne therapies. Antihistamine is a widely used medication to treat several allerg...

The Effect of histamine and some Antihistamine in the motitlity of human semin were studid. It shows that the histamine increases sperm metility, further more H2 antihistamine crimetidine had no effect on sperm motility and classical antihistamines decreased sperm motility , where as the inhibition produced by H antihistamine could be over comed with increasing concentration of histamine. Final...

OBJECTIVES Over-the-counter (OTC) pharmacy medicines are considered relatively safe in contrast to prescribed and illicit substances, but their abuse and addiction potential is increasingly recognised. Those affected represent a hard to reach group, with little known about their experiences. Study objectives were to describe the experiences and views of those self-reporting OTC medicine abuse, ...

UNLABELLED Acoustic rhinometry and rhinomanometry are important tests used to assess nasal function. The degree to which the parameters of these tests are correlated is yet to be established. OBJECTIVE This paper aimed to study the correlations between nasal resistance (NR) and acoustic rhinometry parameters in children and adolescents with allergic rhinitis and controls. METHOD Twenty pati...

background: urticaria is a skin disease characterized by pruritic edematous lesions also called wheals. although these lesions are self-limited they may result in lowered quality of life index. by far, the most recognized mechanisms that trigger the progression of this condition are hypersensitivity reactions. as an herbal therapy, plantago major has been named in several references of persian ...