نتایج جستجو برای: antiglutamic acid decarboxylase anti
تعداد نتایج: 1080061 فیلتر نتایج به سال:
1. Stiff-person syndrome (SPS) is an autoimmune disease characterized by muscle rigidity, episodic muscle spasms, as well as continuous cocontraction of agonist and antagonist muscles. 2. Although a criterion for diagnosis of SPS, anti– glutamic acid decarboxylase (anti-GAD) antibodies can be negative in up to 40% of patients. In absence of antibodies, characteristic EMG findings of continuous ...
Quantum chemical calculations are used to investigate the detailed reaction mechanism of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid (SEPHCHC) synthase (also known as MenD), a thiamin diphosphate-dependent decarboxylase that catalyzes formation SEPHCHC from 2-ketoglutarate and isochorismate. This enzyme is involved in menaquinone biosynthesis pathway M. tuberculosis thoug...
Glutamic acid decarboxylase (GAD) is an intracellular enzyme found in the presynaptic end of nerve terminals that functions to synthesize gamma-aminobutyric (GABA) via decarboxylation. Autoantibodies GAD65 isoform have been high levels neurological disorders including stiff person syndrome (SPS), autoimmune encephalitis, and refractory epilepsy. Low anti-GAD65 also noted type 1 diabetes melli...
background: retinoic acid as one of the most important regulators for cell differentiation was examined in this study for differentiation of human umbilical mesenchymal cells (hucm). methods: after isolation, hucm were evaluated for mesenchymal stem cell properties by flow cytometry and alkaline phosphatase assay. also, doubling time of the cells and their differentiation potential into adipoge...
AIMS/INTRODUCTION The distributer of the anti-glutamic acid decarboxylase antibody assay kit using radioimmunoassay (RIA) recently announced its discontinuation, and proposed an alternative kit using enzyme-linked immunosorbent assay (ELISA). The aim of the present study was to investigate the diagnostic values of the anti-glutamic acid decarboxylase antibody by RIA and ELISA among type 1 diabe...
Background: Aromatic L-amino acid decarboxylase (AADC) deficiency is caused by mutations in the dopa gene leading to reduced AADC enzyme activity; it characterized motor impairments and inability attain developmental milestones.
INTRODUCTION Paraneoplastic cerebellar degeneration is a rare non-metastatic manifestation of malignancy. In this report, to the best of our knowledge we describe for the first time a diagnosis of paraneoplastic cerebellar degeneration several months prior to the diagnosis of clear carcinoma of the uterus. CASE PRESENTATION A 75-year-old Caucasian woman manifested a rapidly progressive cerebe...
Ghrelin and leptin are two hormones that possess multiple functions, including appetite regulation, maintenance of the tissue homeostasis regulation proinflammatory cytokines. A few studies on serum ghrelin levels in autoimmune diseases have exhibited conflicting results. Therefore, present study aimed to investigate relationship between energy balance diseases. Serum were assessed 94 adult pat...
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