Optically inactive gossypol is an effective male antifertility agent in several mammalian species, while optically active (+)-gossypol has no antifertility effect in the rat and hamster. Recently, it was suggested that the mitochondria of spermatogenic cells may be a subcellular target of gossypol. We are reporting the effects of optically inactive gossypol and (+)-gossypol on the respiratory c...

background: hymenocardia acida is traditionally used in african herbal medicine and has numerous therapeutic benefits. but little is known about its potentially negative effects on pregnant women. objective: the aim of the present study was to evaluate the antifertility effect of aqueous ethanolic extract of hymenocardia acida stem bark in female wistar rats. materials and methods: four groups ...

In the present study, Plumbago zeylanica Linn. (Plumbaginaceae) , one of the folk medicinal plants commonly used as antifertility agent was evaluated for its antifertility effect. Five successive solvent extracts, petroleum ether, chloroform, acetone, ethanol and water extracts, of the stems of P. zeylanica were studied on estrous cycle at two dose levels, 200 and 400 mg/kg respectively....

Steroidogenesis plays a key role in the development and maintenance of male reproductive function and fertility. The objective of the present study was to investigate the effect of Carica papaya seed extract on steroidogenesis. The reduced cholesterol levels indicate decreased mobilization towards androgenesis which leads to decreased steroidogenesis and thereby inhibition of spermatogenesis in...

the rising human population, particularly in the developing countries, and the attendant socioeconomic effects necessitates the need for its effective regulation. this study aims at exploring the contraceptive efficacy of the fruit extract of xylopia aethiopica (dunal) a rich, a plant with wide ethnomedicinal, pharmacological and social values, in combating this public health challenge. forty e...

Dried powder of leaf extract of common Indian plant Moringa Oleifera of Moringaceae family was tested experimentally in albino rats in our laboratory for its antifertility activity. Cant per cent abortifacient activity was found when administered orally in aqueous solution at dose of 175 mg/kg body weight daily to Charles foster strain albino rats from days 5-10 post mated.

Ethnobotanical study of antifertility medicinal plants used by the local people in Kathiyavadi village, Vellore District, Tamilnadu, India K. Sathiyaraj, A. Sivaraj, T. Thirumalai, B. Senthilkumar Department of Zoology, Thiruvalluvar University, Serkadu, Vellore-632 106. Tamilnadu, India. Post graduate and Research Department of Zoology, Physiology wing, Voorhees College, Vellore 632001. Tamiln...

Traditional medicines derived from plants play an important role in health care systems all over the world. However, several studies have demonstrated possible fertility disturbs mainly in male and female rats. In this mini review, risks for rat reproduction are briefly described. Correspondence to: Prof. Dr. Romero Brandão-Costa, Department of Morphology and Animal Physiology, Federal Rural Un...

INTRODUCTION: The World Health Organization (WHO) has constituted a population control programme which includes studies on drugs used in traditional medical practices. Medicinal plant products have a long history of indigenous use in India as well as in other countries 1 . Phytotherapy has a very long tradition, although proper scientific explanation is relatively new. In our country as well as...