Both synthetic and catabolic processes determine the serum gamma-globulin level. The rate of gamma-globulin synthesis appears to be the primary factor determining the amount of serum gamma-globulin. Increase of gamma-globulin synthesis (as may occur following immunization or development of plasma cell tumor) elevates the serum gamma-globulin level. This, in turn, accelerates the fractional rate...

The protein of human serum, tentatively designated beta(1C)-globulin, was shown to possess serological activity and to be related to the complement system. Another serum protein (beta(1A)-globulin) was identified as the inactivated form of beta(1C)-globulin. Incubation of fresh serum with various immune precipitates or with soluble gamma-globulin aggregates at 37 degrees C. resulted in the remo...

The serological and physicochemical properties of the following three forms of human anti-gamma-globulin factors were compared: (a) rheumatoid factors; (b) Milgrom type anti-gamma-globulin factors; and (c) factors directed against an antigen in human gammaG-globulin that is hidden in the intact molecule and revealed by enzymatic digestion at low pH. The property common to these factors is abili...

1. Gamma globulin metabolism and distribution were studied employing rabbit gamma globulin (RGG)I(131) 24 times in 13 control rabbits. Similar studies were performed before and during the ananmestic response in 4 rabbits previously sensitized with a polyvalent pneumococcal vaccine. 2. During the ananmestic response, gamma-globulin levels increased from 1.0 to 6.0 gm/100 ml, and the gamma-globul...

The transition from animal- to plant-derived dietary proteins is of global importance. Plant are normally processed into extracts, and due the type process, globulin class mainly extracted. Such extractions have several waste streams, containing another protein class: albumins. Here, we show that plant albumins good functionality. We compared interfacial foaming properties globulins mung bean, ...

The anticryptococcal activity of peripheral blood polymorphonuclear leukocytes (PMN) and monocytes was compared on plastic versus human umbilical vein endothelial cell surfaces. Various amounts of PMN and monocytes were incubated on plastic or endothelial surfaces and then challenged for 18 h with Cryptococcus neoformans. Both phagocyte populations exhibited significantly more anticryptococcal ...

We recently reported that rabbit antithymocyte globulin was markedly inferior to horse antithymocyte globulin as a primary treatment for severe aplastic anemia. Here we expand on our findings in this unique cohort of patients. Rabbit antithymocyte globulin was detectable in plasma for longer periods than horse antithymocyte globulin; rabbit antithymocyte globulin in plasma retained functional c...

The aim of this study was to determine for reference purposes the values of serum albumin, alpha 1-globulin, alpha 2-globulin, beta-globulin, gamma-globulin, and alpha-lipoprotein (high density lipoprotein), pre-beta-lipoprotein (very low density lipoprotein) and beta-lipoprotein (low density lipoprotein) fractions of normal ostriches (Struthio camelus) in Turkey. Five male and five female ostr...

HE PROTEINS OF NORMAL HUMAN SERUM have been resolved both by moving-boundary and filter-paper electrophoresis chiefly into five components: albumin, , , , and’ globulins. In various disease states, by both technics, other protein components have been described. A component migrating between 22 globulin and beta globulin has been observed by Block et al. (1) in primary systemic amyloidosis and w...