نتایج جستجو برای: anticholinergic syndrome
تعداد نتایج: 623855 فیلتر نتایج به سال:
McCubbin, T. D., Brown, J. H., Dewar, K. M. S., Jones, C. J., and Spence, A. A. (1979). Glycopyrrolate as a premedicant: comparison with atropine. Br. J. Anaesth., 51, 885. Rupreht, J. (1980). Physostigmine rcversaj of diazepam. Anesthesiology, (in press). Dworacek, B. (1976). Central anticholinergic syndrome in anaesthetic practice. Acta Anaesthesiol. Belg., 27, 45. Selenati, A. (1979). Recett...
BACKGROUND Adverse effects of anticholinergic medications may contribute to events such as falls, delirium, and cognitive impairment in older patients. To further assess this risk, we developed the Anticholinergic Risk Scale (ARS), a ranked categorical list of commonly prescribed medications with anticholinergic potential. The objective of this study was to determine if the ARS score could be u...
McCubbin, T. D., Brown, J. H., Dewar, K. M. S., Jones, C. J., and Spence, A. A. (1979). Glycopyrrolate as a premedicant: comparison with atropine. Br. J. Anaesth., 51, 885. Rupreht, J. (1980). Physostigmine rcversaj of diazepam. Anesthesiology, (in press). Dworacek, B. (1976). Central anticholinergic syndrome in anaesthetic practice. Acta Anaesthesiol. Belg., 27, 45. Selenati, A. (1979). Recett...
We present a case of acute tolterodine overdose with anticholinergic toxidrome including drowsiness, confusion and pyrexia. Tolterodine was commonly used in recent years for the treatment of overactive bladder syndrome. Experience with acute tolterodine poisoning was limited. The pharmacology, clinical use and side effects of tolterodine were reviewed. The clinical manifestations, toxicology an...
CONTEXT The cognitive side effects of medications with anticholinergic activity have been documented among older adults in a variety of clinical settings. However, there has been no systematic confirmation that acute or chronic prescribing of such medications lead to transient or permanent adverse cognitive outcomes. OBJECTIVE Evaluate the existing evidence regarding the effects of anticholin...
Overactive bladder (OAB) is a medical syndrome defined by symptoms of urgency, with or without urge urinary incontinence (any involuntary loss of urine), usually with frequency and nocturia. Although anticholinergic agents have been the first-line treatment for OAB for many years, the efficacious pharmacologic management of this condition has been compromised by concerns regarding tolerability....
Anticholinergic medications such as Trihexyphenidyl; Biperidine are widely prescribed to prevent or to treat extrapyramidal side effects produced by neuroleptic drugs. Concomitant use of anticholinergic drugs is more common with the first generation antipsychotic medications. There is a considerable body of data suggesting that anticholinergic drugs have a potential of abuse. In this article, w...
Overactive bladder (OAB) is an age-related syndrome often associated with urinary incontinence. Symptoms of OAB, such as urgency, frequency, and nocturia, can be treated effectively with inhibitors of muscarinic acetylcholine receptors. Antimuscarinic agents promote relaxation of the detrusor muscle and may modulate afferent neuronal signals involved in the regulation of the micturition reflex....
OBJECTIVES To explore the association between the number of physicians providing care and anticholinergic drug burden in older persons newly initiated on cholinesterase inhibitor therapy for the management of dementia. DESIGN Population-based cross-sectional study. SETTING Community and long-term care, Ontario, Canada. PARTICIPANTS Community-dwelling (n = 79,067, mean age 81.0, 60.8% fema...
One characteristic neuropathological feature of Alzheimer's disease (AD) is profound neuronal loss in the nucleus basalis of Meynert, the major source of cholinergic innervation of the cerebral cortex. Clinically, anticholinergic activity causes a decline in cognitive function and increases the risk of dementia, thus possibly enhancing AD pathologies and neurodegeneration. Until now there has b...
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