نتایج جستجو برای: anti tumor
تعداد نتایج: 748612 فیلتر نتایج به سال:
Erianin, a phytoestrogen with therapeutic potential, is one of the major active components Dendrobll caulis. Erianin has variety pharmacological effects, such as anti-tumor, anti-inflammatory, anti-diabetic retinopathy, anti-psoriasis, and antibacterial effects. Especially, in regard to anti-tumor effect erianin, underlying molecular mechanism been partly clarified. In fact, numerous actions er...
objective: recent evidences suggest that tumors arise from a small subpopulation of cells, the cancer stem cells (cscs) or tumor initiating cells. cscs are able to resist the conventional methods of cancer therapy due to existence of abc transporters on their surface. this leads to csc resistance and maintenance resulting in post-treatment relapse and metastasis. therefore, precise identificati...
There are many patents for magnetic nanoparticles as tumor resonance imaging enhancers, but the gadolinium complexes commonly used in clinic difficult to target diseased tissues, while nanoliposomes ideal carriers anti-tumor drugs.
Immune checkpoint inhibitors have revolutionized the treatment of patients with advanced and metastatic melanoma led to prolonged overall survival. However, long-term responses are still limited few patients, where tumor-specific effector T cells at tumor sites considered predictors for success. This raises question new strategies. We were recently able show in preclinical models, that targeted...
Background: In addition to passive immunotherapy using anti-HER2 monoclonal antibodies, active immunotherapy via HER2 targeting is an interesting approach to inducing specific anti-tumor immune responses. We have recently reported the immunogenicity of HER2 subdomains following DNA immunization and HER2 protein boosting. In the present study, we evaluated the immunogenicity of different HER2 ex...
iranian castor bean lectin was isolated and purified by several column chromatography methods. then, the sugar and amino acid content of the purified lectin was identified. castor bean lectin has some anti tumor and anti leukemia action. thus it may be used commercially for medical and biochemical purposes.
ایمونوتوکسینها برای درمان سرطان در حال توسعه هستند. آنها از آنتی بادیهای متصل به توکسین مانند اگزوتوکسین پسودوموناس تشکیل میشوند. از طرف دیگر فاکتور رشد اندوتلیال عروقی (vegf) در آنژیوژنزیس تومور نقش دارد و مهار vegfr-2 آنژیوژنزیس و رشد تومور را مهار میکند. هدف از این مطالعه تولید ایمونوتوکسین anti-vegfr2/rpe38، ارزیابی فعالیت سایتوتوکسیسیتی و مکانیسم عملکرد آن در in vitro بود. برای تولید ایمون...
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