inflammation is one of the symptoms of many common and harmful diseases. as it is incurable through chemical drugs, the study on this ailment using new methods and drugs seems necessary. in addition, the adverse effects of the present anti-inflammatory drugs like nsaids and glucocorticoid appeared in the long time use make such study more demanded. accordingly, in this study we examined the eff...

inflammation is a part of the non-specific immune response which occurs in reaction to any type of injury. medicinal mushrooms have had application in various disorders including cancer, liver injuries, inflammation and diabetes. in the present study, the anti-inflammatory effects of the aqueous extracts of medicinal mushrooms (fomes fomentarius, ganoderma applanatum and trametes hirsuta) were ...

background: inflammation is a dynamic process that is elicited in response to various harmful stimulantsthat may threaten the well-being of the host. herbs have been traditionally used as anti-inflammatory agents since very early times. rubia tinctorum l. is one of these herbs that havebeen used for treating inflammatory diseases in iranian traditional medicine. objective: this study aims at co...

objectives: iron chelators, such as maltol and kojic acid, have antioxidant and anti-inflammatory properties. they may have beneficial effects on inflammatory bowel disease (ibd) because iron can develop and aggravate inflammation in ibd. in the present study, the effect of selected iron chelators and anti-oxidants were evaluated on a model of trinitrobenzene sulfonic acid (tnbs)-induced coliti...

purpose: to report a case of delayed corneal perforation secondary to topical diclofenac usage after myopic lasek and review of literature. patients and findings: a 25-year-old female with history of myopic lasek 2 months before referred to her surgeon with epithelial defect, stromal thinning and infiltration. she was treated with antimicrobial medications for infectious keratitis for one week....

a series of five-membered heterocyclic rings were synthesized by the reaction between benzoyl chloride and various chlolro-nitro-benzoyl chlorides and semi carbazide to form (c1-c7) compounds and was tested for their anti-inflammatory activity determined by rat-paw-oedema method. all the synthesis compounds have been characterized by 1hnmr, ir and mass spectral data. the compounds were purified...

diclofenac sodium has been used for its anti-inflammatory actions for about 28 years, but since all the non-steroidal anti-inflammatory drugs (nsaids) suffer from the lethal gastro intestinal (gi) toxicities, diclofenac sodium is not an exception. the free –cooh group is thought to be responsible for the gi toxicity associated with all traditional nsaids. in the present research, the main motto...

the aim of the present study was to investigate the potential of nanoemulsion formulation for topical delivery of clobetasol propionate (cp) using algal oil (containing omega-3 fatty acids) as the oil phase. cp has anti-inflammatory, immunomodulatory and antiproliferative activities. however, its clinical use is restricted to some extent due to its poor permeability across the skin. algal oil w...

background : ulcerative colitis an inflammatory bowel disease (ibd) and chronically idiopathic immune related that associates with extraintestinal manifestations such as arthritis. despite of the highly specificity ofanti-cyclic citrullinated peptide (ccp) antibodies for rheumatoid arthritis, their role in ibd remains unclear . there are only a few studies on the prevalence of anti-ccp antibodi...

alzheimer's disease (ad) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. the exact cause of alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. this brings in mind using non-steroidal anti-inflammatory drugs (nsaid) as treatment or prevention of the dise...