نتایج جستجو برای: anti angiogenesis

تعداد نتایج: 399393  

ژورنال: دانشور پزشکی 2016
حسن‌پورعزتی, , مجیدی‌فرد, ,

Background and Objective: Recently, it has been shown that some naked metal nanoparticles have angiogenesis potential. In the present study, the anti-angiogenesis property of bare manganese oxide (MnO2) nanoparticles was investigated on chicken chorioallantoic membrane (CAM). Materials and Methods: Fifty hen fertilized eggs were divided into five groups (n=10); the control and experiment...

2013
Ching-Chiu Liu Zan Shen Hsiang-Fu Kung Marie CM Lin

Since the relationship between angiogenesis and tumor growth was established by Folkman in 1971, scientists have made efforts exploring the possibilities in treating cancer by targeting angiogenesis. Inhibition of angiogenesis growth factors and administration of angiogenesis inhibitors are the basics of antiangiogenesis therapy. Transfer of anti-angiogenesis genes has received attention recent...

Journal: :Scientia Pharmaceutica 2021

Colorectal cancer (CRC) aggressiveness is caused by angiogenesis which promotes the growth and metastasis associated with poor prognosis survival. The vascular endothelial factor-A (VEGF-A) its receptor (VEGFR-2) form major signaling pathway in angiogenesis. This study aimed to investigate anti-angiogenesis activity of quercetin both colorectal cells cells. tube formation human vein (HUVECs) wa...

Journal: :British journal of pharmacology 2012
G M Palmer Z Tiran Z Zhou M E Capozzi W Park C Coletta A Pyriochou Y Kliger O Levy I Borukhov M W Dewhirst G Rotman J S Penn A Papapetropoulos

BACKGROUND AND PURPOSE Pathological angiogenesis is associated with various human diseases, such as cancer, autoimmune diseases and retinopathy. The angiopoietin (Ang)-Tie2 system plays critical roles in several steps of angiogenic remodelling. Here, we have investigated the anti-angiogenic effect of a novel angiopoietin-derived peptide. EXPERIMENTAL APPROACH Using computational methods, we i...

Journal: :VNU Journal of Science: Medical and Pharmaceutical Sciences 2019

2014
Jun-Xiu Liu Min-Qi Luo Meng Xia Qi Wu Si-Mei Long Yaohua Hu Guang-Chun Gao Xiao-Li Yao Mian He Huanxing Su Xiong-Ming Luo Shu-Zhong Yao

Angiogenesis is the formation of blood vessels from pre-existing vasculature. Excessive or uncontrolled angiogenesis is a major contributor to many pathological conditions whereas inhibition of aberrant angiogenesis is beneficial to patients with pathological angiogenesis. Catunaregin is a core of novel marine compound isolated from mangrove associate. The potential anti-angiogenesis of catunar...

Fatemeh Rajabi Mitra Heidarpour, Mohammad Ali Rajabi, Parvin Rajabi Dehnavi

  Background and Objective: Angiogenesis is a complex program of several steps and it is tightly regulated by pro- and anti-angiogenic factors. Angiogenesis is one of the key elements in cutaneous wound healing and skin cancers. Estrogen seems to have positive modulating effect on cutaneous wound healing and this effect may be explained by its angiogenic properties. This study aims to investig...

Journal: :The Keio Journal of Medicine 2012

Journal: :Folia Pharmacologica Japonica 2003

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