Lack of visual input early in life results in occipital cortical responses to auditory and tactile stimuli. However, it remains unclear whether cross-modal plasticity also occurs in subcortical pathways. With the use of functional magnetic resonance imaging, auditory responses were compared across individuals with congenital anophthalmia (absence of eyes), those with early onset (in the first f...

We placed negative electrodes on the body and positive electrodes at the medial and lateral canthi, measured their potentials separately, evaluated their characteristics, and analyzed cross-talk. We recorded EOG in 6 normal subjects and found the following. The potential at the medial was lower than that at the lateral canthus in the bilateral eyes. The polarity of waves at the lateral was reve...

Anophthalmia and serious microphthalmia are conditions characterized by the complete lack of the primary optic vesicle or the presence of the rudimentary eye-like structure. These are rare prenatal conditions, yet diagnoses remain a challenge in Black African areas, raising a major concerns surrounding care after birth. This paper reports a case of anophthalmia and serious microphthalmia, the d...

Neurochemical changes in the pericalcarine cortex in congenital blindness 1 due to bilateral anophthalmia 2 Abbreviated title: Neurochemical changes in bilateral anophthalmia 3 4 Gaelle S L Coullon, Uzay Emir, Ione Fine, Kate E Watkins, Holly Bridge. 5 6 1 FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, 7 John Radcliffe Hospital, Oxford 8 2 Department of Psych...

We report a patient with anal atresia, anophthalmia and intestinal neuronal dysplasia type A.

This review provides a synthesis that combines data from classical experimentation and recent advances in our understanding of early eye development. Emphasis is placed on the events that underlie and direct neural retina formation and lens induction. Understanding these events represents a longstanding problem in developmental biology. Early interest can be attributed to the curiosity generate...

AIM To analyse the extent of bony orbital volume reduction after enucleation in humans. METHODS Volumetric studies on bony orbital volumes based on three dimensional reconstructions acquired from high resolution computed tomograph (CT) scans were performed in 29 patients with acquired anophthalmia and four patients before enucleation (controls). Eight patients (follow up 25-52 years) were enu...

BACKGROUND The northeastern region (NER) of India is geographically isolated and ethno-culturally different from the rest of the country. There is lacuna regarding the data on causes of blindness and severe visual impairment in children from this region. AIM To determine the causes of severe visual impairment and blindness amongst children from schools for the blind in the four states of NER ...