Purpose To compare the anterior and posterior choroid thickness (ACT and PCT, respectively) in primary open-angle glaucoma (POAG), primary angle-closure disease (PACD), and healthy control subjects. Methods A total of 29 POAG patients (56 eyes), 37 PACD patients (64 eyes), and 34 healthy volunteers (68 eyes) were enrolled in this study; 50 POAG eyes were divided into 25 early/moderate-stage a...

purpose : to compare the serum homocysteine (hcy) level in healthy control individuals and in patient with primary open angle glaucoma (poag) and pseudoexfoliative glaucoma (pexg) methods : in this cross sectional study, 79 subjects including 36 patients with pexg, 23 patients with poag, and 20 matched healthy control individuals were recruited. those who used alcohol and mediations affecting h...

PURPOSE Despite the different etiology of primary open angle glaucoma (POAG), primary angle closure glaucoma (PACG), and pseudoexfoliative glaucoma (PEXG), several studies have suggested that these forms of glaucoma have overlapping genetic risk factors. Therefore, the aim of this study was to evaluate the role of genetic variants recently associated with POAG in different types of glaucoma in ...

PURPOSE To report the pattern of glaucoma among Saudi patients who were presented to King Abdul Aziz University Hospital (KAUH). METHODS All glaucoma or glaucoma suspect patients who were presented to KAUH from 2006 to 2008 were included; medical files of all patients were retrieved and evaluated through standardized international guidelines. Collected data included: age, sex, laterality, int...

PURPOSE To identify myocilin (MYOC) and cytochrome P450, family 1, subfamily B, polypeptide 1 (CYP1B1) mutations in a Spanish population with different clinical forms of familial glaucoma or ocular hypertension (OHT). METHODS Index patients from 226 families participated in this study. Patients were diagnosed with familial glaucoma or OHT by complete ophthalmologic examination. Screening for ...

Copyright: © 2017. The Author(s). Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License. Introduction Glaucoma is an optic neuropathy that sometimes results in irreversible blindness.1 After cataracts, glaucoma is the second most prevalent cause of global blindness,2 and it is estimated that almost 80 million people worldwide will be affected by this optic neurop...

PURPOSE The current study was undertaken to investigate whether glaucoma affects the sleep quality and whether there is any difference between patients with primary glaucoma (primary open angle glaucoma, POAG and primary angle-closure glaucoma, PACG) and healthy subjects, using a validated self-rated questionnaire, the Pittsburgh Sleep Quality Index (PSQI). METHODS The sleep quality of patien...

AIMS To investigate the usefulness of the scanning laser polarimeter (GDx; GDx Nerve Fiber Analyzer) for glaucoma detection in the Japanese population, and to investigate the difference in the thickness of retinal nerve fibre layer (RNFL) between normal tension glaucoma (NTG) and primary open angle glaucoma (POAG). METHODS 69 eyes of 69 normal subjects and 115 eyes of 115 chronic open angle g...

PURPOSE The aim of this study was to characterize a representative sample of the Peruvian population suffering open-angle glaucoma (OAG) with respect to the myocilin gene (MYOC) mutations, glaucoma phenotype, and ancestry for future glaucoma risk assessment. METHODS DNA samples from 414 unrelated Peruvian subjects, including 205 open-angle glaucoma cases (10 juvenile glaucoma [JOAG], 19 norma...

Purpose: Glaucoma, the second leading cause of blindness, is characterized by changes in the optic disc and visual field defects. The elevated intraocular pressure was considered the prime factor responsible for the glaucomatous optic neuropathy involving death of retinal ganglion cells and their axons. Extensive investigations into the pathophysiology of glaucoma now reveal the role of multipl...