Alopecia areata is a non-scarring form of alopecia that can be localized or widespread. Its etiology is unknown, but immunological factors are implicated in its pathogenesis. With the more frequent use of anti TNFα biologic drugs, some alopecia areata cases during their use have been described. We report a case of universal alopecia in a patient with rheumatoid arthritis while using adalimumab ...

and male alopecia [1–4] . The prerequisite for delivering appropriate patient care is an understanding of the pathologic dynamics of hair loss and a potential multitude of causal relationships. Once the diagnosis is certain, treatment appropriate for that diagnosis is likely to control the problem. Ultimately, the best way to alleviate the emotional distress related to hair loss is to effective...

BACKGROUND Alopecia can be a manifestation of mycosis fungoides (MF); however, the prevalence is unknown. AIMS We sought to describe the clinicopathologic presentation of alopecia in patients with diagnosis of MF. METHODS A retrospective analysis of patients with biopsy-proven MF, who were evaluated at our cancer center from 2002 to 2012, was performed to identify patients with alopecia. ...

Alopecia areata is thought to be a T-cell mediated and cytokine mediated autoimmune disease that results in non-scarring hair loss. Poliosis has been described as a localized depigmentation of hair caused by a deficiency of melanin in hair follicles. A 57-year-old man with a history of alopecia areata developed white hair regrowth in areas of previous hair loss. We retrospectively reviewed the ...

To cite: Lacarrubba F, Micali G. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013202918 DESCRIPTION A 4-year-old Caucasian girl presented with a 1-year history of asymptomatic, localised alopecia. Examination revealed a 3.5×3.0 cm area of alopecia over the right frontotemporal region of the scalp, with its apex towards the vertex (figure 1). There was no scali...

BACKGROUND Alopecia areata is the most common cause of localized, nonscarring alopecia. Unfortunately, there are few data regarding clinical features and epidemiology of alopecia areata in Korean patients, and its clinical course and treatment response rates are unpredictable. OBJECTIVE This study strived to investigate the differences in clinical profiles according to disease severity and to...

Hair loss or alopecia is a common and distressing clinical complaint in the primary care setting and can arise from heterogeneous etiologies. In the pediatric population, hair loss often presents with patterns that are different from that of their adult counterparts. Given the psychosocial complications that may arise from pediatric alopecia, prompt diagnosis and management is particularly impo...

Alopecia areata is one of the most common autoimmune diseases resulting from T cell-mediated damage of hair follicles. CD8+ T cells infiltrate hair follicles and are responsible for destruction of hair follicles. However the underlying mechanisms for hair loss remain still obscure. In the present study, we identified that suppressor of cytokine signaling-3 (SOCS3), a classical inhibitor of cyto...

There are numerous dermatoses which may cause cicatricial alopecia when localized on the scalp, such as chronic discoid lupus erythematosus (DLE), lichen planus, graft-versus-host disease, dermatomyositis, scleroderma, cicatricial pemphigoid, porphyria cutanea tarda, follicular mucinosis, perifolliculitis capitis abscedens, lichen sclerosus et atrophicus, necrobiosis lipoidica, sarcoidosis, etc...