The striatum is involved in the control of appetitively motivated behavior. We found previously that tonically active neurons (TANs) in the monkey striatum show discriminative responses to different stimuli that are appetitive or aversive. However, these differential responses may reflect the sensory qualities of the stimulus rather than its motivational value. In the present study, we sought t...

The detection of differences between predictions and actual outcomes is important for associative learning and for selecting actions according to their potential future reward. There are reports that tonically active neurons (TANs) in the primate striatum may carry information about errors in the prediction of rewards. However, this property seems to be expressed in classical conditioning tasks...

Advances in the technology of low cost solid-state inertial sensors have brought the price for a inertial measurement unit (IMU) down to the $ 10,000 level. Such an IMU, Systron Donners’ MotionPak, has been purchased by the Institute of Geodesy and Navigation (IfEN) in order to develop an integrated GPS/INS attitude determination system. As GPS component for the integrated system, IfEN has sele...

Tonically active neurons (TANs)--presumably, striatal cholinergic interneurons--exert a strong influence on striatal information processing. Primate studies often describe a characteristic TAN response comprising suppressed activity followed by rebound firing that occasionally is preceded by a brief activation. By contrast, studies in behaving rats report pronounced excitation during movement. ...

Wir beschreiben ein Verfahren, das die authentische Online-Übertragung von Transaktionen ermöglicht, ohne dass ein vertrauenswürdiger Zustand des Endgeräts (PC) vorausgesetzt wird. Das Verfahren verwendet visuelle Kryptographie anstelle von Transaktionsnummern (TANs), wie sie im Online-Banking-Bereich verbreitet sind.

Neutrophils have a traditional role in inflammatory process and act as the first line of defense against infections. Although their contribution to tumorigenesis and progression is still controversial, accumulating evidence recently has demonstrated that tumor-associated neutrophils (TANs) play a key role in multiple aspects of cancer biology. Here, we detected that chemokine CXCL1 was dramatic...

Midbrain dopamine and striatal tonically active neurons (TANs, presumed acetylcholine interneurons) signal behavioral significance of environmental events. Since striatal dopamine and acetylcholine affect plasticity of cortico-striatal transmission and are both crucial to learning, they may serve as teachers in the basal ganglia circuits. We recorded from both neuronal populations in monkeys pe...

BACKGROUND & AIMS Chronic inflammation is a major etiological factor for hepatocellular carcinoma (HCC), but how immune cells respond in the initiation of hepatocarcinogenesis remains uncharacterized. This study aims to investigate the response and roles of neutrophils in early hepatocarcinogenesis. METHODS By inducible expression of oncogenic kras(V12) in hepatocytes in transgenic zebrafish ...