background the prevalence of celiac disease (cd) is remarkably varied in down syndrome(ds)patientscompared with other diseases.  this study aimed to assess celiac disease prevalence in down syndrome children with and without congenital heart defects (chd) and its comparison with controls. materials and methods this case-control study was performed at a single center on 132 participants in three...

Objective: The present study was carried out to study the relationship between sensation seeking and social skills in two groups of school age patients Down-Syndrome (DS) and Autism Disorder (DS).  Methods: This is a descriptive-analytic and correlation study in which all participants were of primary school age (10 to 13 years) with Down-Syndrome and Autism Disorder of autism spectrum disord...

Objective: This study aimed to evaluate the quality of life and related factors in mothers of children with Down syndrome. Methods: The study method was correlation-survey (sectional). Sampling was based on the available population. The research population consisted of all mothers of children with Down syndrome referred to the Down Syndrome Center: out of them 70 mothers of chil...

we report three cases of asymptomatic celiac disease identified in children with down syndrome after being screened at around twenty-four months of age.  these cases raise the question as to what age is screening for celiac disease indicated in a child with down syndrome and no symptoms.

Objectives: Down syndrome is the most common chrosomal disorder in which the fine and gross motor skills due to lack of proper sensory experience are disturbed. The role of dexterity in activity of daily living, interaction with environment and independency is quiet crucial in Down syndrome. Therefore, the aim of this study was to investigate the effects of simultaneous application of superfici...

Background & Aims: Previous studies have indicated significant differences in vocal parameters between children with Down syndrome and normal children, but there are challenges about these differences. In this study vocal parameters and Maximum Phonation Time (MPT) in adults with Down syndrome have been investigated. Method: This cross-sectional and analytic study was performed on 22 adults wit...

objective: the influence of cholinergic drugs on lithium-induced statedependent learning has been investigated in adult male mice. method: a single-trial step-down inhibitory avoidance task was selected. the drugs used in the study were lithium chloride physostigmine , nicotine hydrogen tartrate and scopolamine hydrobromide, atropine sulphate. the drugs were administrated through the peritoneal...