Multiple myeloma (MM) is characterized by a clonal proliferation of malignant plasma cells in the bone marrow which secrete monoclonal immunoglobulins (paraproteins) into the serum. Clinical characteristics are lytic bone lesions, impairment of normal hematopoiesis and kidney function. It is accepted that all MM cases are preceded by an asymptomatic expansion of clonal plasma cells designated m...

Human aromatase is responsible for the last step of estrogen biosynthesis, for the aromatization of ring A of androstenedione (ASD) or testosterone. In this work the mechanism of aromatization was studied using gas phase and hybrid QM/MM calculations. It is shown that human aromatase can efficiently catalyze the aromatization process via a Compound I (or Compound II) mediated pathway. The natur...

in this research the effect of potrecine, spermine and spermidine on the postharvest life of cut red carnation (corsa) and some physiological trait was investigated in horticultural lab of azad university. therefore, an experiment based on completely randomized block design with tree levels of putrescine (1, 2 and 3) mm and spermidine (0.5, 1 and 2) and spermine (1, 2 and 3) mm with 3 replicati...