Reference models, whose aim is to capture domain knowledge, can assist in the adequate design of enterprise specific business processes. In complex organisations, business processes can be locally designed by specific organisational units. However, in order to be adequate, these processes should meet the local needs while maintaining the organisational standards. For this purpose, we propose to...

Ancient (proto-) Bulgarians have long been thought of as a Turkic population. However, evidence found in the past three decades shows that this is not the case. Until now, this evidence has not included ancient mitochondrial DNA (mtDNA) analysis. To fill this void, we collected human remains from the 8th to the 10th century AD located in three necropolises in Bulgaria: Nojarevo (Silistra region...

The terminal Pleistocene and Early Holocene, a period from 15 000 to 18 000 Before Present (BP), was critical in establishing the current Holarctic fauna, with temperate-climate species largely replacing cold-adapted ones at mid-latitudes. However, the timing and nature of this process remain unclear for many taxa, a point that impacts on current and future management strategies. Here, we use a...

Analytic hierarchy process (AHP) is a frequently used method for ranking alternatives. The alternatives to be ranked are modeled based on a set of criteria. The ranking computed by AHP is trusted on faith notwithstanding the fact that a model is an approximation and liable to failure. We present a model to estimate the trust in the AHP ranking. The model helps in determining if it is prudent to...

Post-modernism and recent critical theory has sought to deconstruct the role of particular ‘Great Traditions’ and ‘Grand Narratives’ as privileged accounts of world affairs, contemporary and historical. In spite of this, such narratives, even if poorly understood, remain at the heart of much public debate and continue to shape national and global policies. These traditions, linked to elements o...

The colonization of the human environment by plants, and the consequent evolution of domesticated forms is increasingly being viewed as a co-evolutionary plant-human process that occurred over a long time period, with evidence for the co-evolutionary relationship between plants and humans reaching ever deeper into the hominin past. This developing view is characterized by a change in emphasis o...

The transition from hunting and gathering to farming involved profound cultural and technological changes. In Western and Central Europe, these changes occurred rapidly and synchronously after the arrival of early farmers of Anatolian origin [1-3], who largely replaced the local Mesolithic hunter-gatherers [1, 4-6]. Further east, in the Baltic region, the transition was gradual, with little or ...

Working together in groups may be beneficial if compared to isolated efforts. Yet this is true only if all group members contribute to the success. If not, group efforts may act detrimentally on the fitness of their members. Here we study the evolution of cooperation in public-goods games on scale-free networks that are subject to deletion of links connected to the highest-degree individuals, i...

In this article, I model how a problem-posing framework can be used to enhance our abilities to systematically generate mathematical problems by modifying the attributes of a given problem. The problem-posing model calls for the application of the following fundamental mathematical processes: proving, reversing, specializing, generalizing, and extending. The given problem turned out to be a ric...

From the Clinical Pathological Conference Series, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston (J.M.C., J.T.K., B.D.L., J.L.); and the Department of Medicine, Division of Hematology/ Oncology, University of Pennsylvania, Philadelphia (A.C.). Address reprint requests to Dr. Loscalzo at the Department of Medicine, Brigham and Women’s Hospital, Harvard Medic...