Fourteen commercial soft drinks have been analyzed using colorimetric sensor arrays made from a set of 25 chemically responsive dyes printed on a hydrophobic membrane. Digital imaging of the dye array before and after immersion provides a color change profile as a unique fingerprint for each specific analyte. The digital data library generated was analyzed with statistical and chemometric metho...

Prostate cancer (PCa) cells use matrix metalloproteinases (MMPs) to degrade tissue during invasion. Perlecan/HSPG2 is degraded at basement membranes, in reactive stroma and in bone marrow during metastasis. We previously showed MMP-7 efficiently degrades perlecan. We now analyzed PCa tissue and serum from 288 prostatectomy patients of various Gleason grades to decipher the relationship between ...

OBJECTIVES Prostate cancer (PCa) represents one of the most complicated human tumors and, like many others malignancies, arises from progressive genetic and epigenetic alterations. Among all recognized epigenetic alterations, aberrant DNA methylation (hypo- and hypermethylation) is the most important and the best characterized change in PCa. BACKGROUND We analyzed GSTP1, APC and RASSF1 gene p...

We propose shiny analysis framework accompanied with makeup deterioration using normalized facial images (MaVIC and the corresponding makeup-deteriorated data sets). These images are analyzed and reconstructed based on principal component analysis (PCA) and then the differential ones between the reconstruction images with different numbers of PCA components can be generated. The shiny Eigen-fac...

Epigenetic changes have been suggested to drive prostate cancer (PCa) development and progression. Therefore, in this study, we aimed to identify novel epigenetics-related genes in PCa tissues, and to examine their expression in metastatic PCa cell lines. We analyzed the expression of epigenetics-related genes via a clustering analysis based on ge...

To identify appropriate candidates for aggressive treatment such as radical prostatectomy or radiation therapy of localized prostate cancer (PCa), novel predictive biomarkers of PCa aggressiveness are essential. Core2 β-1,6-N-acetylglucosaminyltransferase-1 (GCNT1) is a key enzyme that forms core 2-branched O-glycans. Its expression is associated with the progression of several cancers. We esta...

Materials and Methods: To detect the expression of VTN as a potential marker for PCa diagnosis and prognosis, immunohistochemistry was performed on the tissues of 32 patients with metastatic PCa (PCaM), 34 patients with PCa without metastasis (PCa), and 41 patients with benign prostatic hyperplasia (BPH). The sera were then subjected to Western blot analysis. All cases were subsequently examine...

The network traffic data used to build an intrusion detection system is frequently enormous and redundant with important useless information which decreases IDS efficiency. In order to overcome this problem, we have to reduce as much as possible this meaningless information from the original high dimensional data. To do this, we have compared the performance of two features reduction techniques...

Process capability analysis (PCA) is the ability of a process that measures the degree of providing customer expectations. Generally, the expectations of customer have been defined by using specification limits. A process capability index (PCI) summarizes ability of process to conform specification limits. Generally, this comparison is made by analyzing ratio of specification limits and six-sig...