Background: Antimicrobial resistance (AMR) in bacteria is an increasing health concern. The spread of AMR bacteria (AMRB) between animals and humans via the food chain and the exchange of AMR genes requires holistic approaches for risk mitigation. The AMRB exposure of humans via food is currently only poorly understood leaving an important gap for intervention design. Method: This study aimed t...

The emergence of multiple-antibiotic-resistance bacteria is increasing, which is a particular concern on livestock farms. We previously isolated 1,347 antimicrobial-resistant (AMR) Escherichia coli strains from the feces of beef cattle on 14 Japanese farms. In the present study, the genetic backgrounds and phylogenetic relationships of 45 AMR isolates were characterized by the chromosome phylot...

BACKGROUND Antimicrobial resistance (AMR) has reached an end point, prompting a worldwide scare as no new antibiotics are in the pipeline, particularly for treatment of Gram-negative bacteria. To prevent further development and spread of AMR and to inform empirical treatment guidelines, surveillance of AMR is necessary. OBJECTIVE We aim to provide a framework for a stepwise approach toward im...

OBJECTIVES MRSA is a major antimicrobial resistance (AMR) pathogen. The reservoir of infecting isolates is colonization, which is the site of evolutionary selection. The aim was to identify if AMRs in colonizing MRSA populations diversified and potential mechanisms of resistance gene transfer in vivo. METHODS Nasal swabs from 38 MRSA carriers admitted to hospital were plated and 20 individual...

We are currently working with several research groups who use adaptive mesh refinement, AMR, techniques for calculations in computational fluid dynamics and cosmology. The computational fluid dynamics group needed a visualization tool to visualize AMR data and to distribute with their AMR library. Since none of the widely available visualization systems directly supported visualizing AMR data, ...

Due to low cost, low-power, and scalability, ZigBee is considered an efficient wireless AMR infrastructure. However, these characteristics of ZigBee can make the devices more vulnerable to unexpected error environments. In this paper, a fault-tolerant wireless AMR network (FWAMR) is proposed, which is designed to improve the robustness of the conventional ZigBee-based AMR systems by coping well...

In this paper, we introduce an Abstract Meaning Representation (AMR) to Dependency Parse aligner. Alignment is a preliminary step for AMR parsing, and our aligner improves current AMR parser performance. Our aligner involves several different features, including named entity tags and semantic role labels, and uses Expectation-Maximization training. Results show that our aligner reaches an 87.1%...

BACKGROUND Antimicrobial resistance (AMR) of infectious agents is a growing concern for public health organizations. Given the complexity of this issue and how widespread the problem has become, resources are often insufficient to address all concerns, thus prioritization of AMR pathogens is essential for the optimal allocation of risk management attention. Since the epidemiology of AMR pathoge...

• Thailand has actively contributed to setting the global agenda on antimicrobial resistance • The national strategic plan on antimicrobial resistance (2017-21) promotes multisectoral collaboration to reduce antimicrobial consumption and AMR morbidity and improve public awareness • Strengthening surveillance systems to measure the burden of AMR and the effect of policies must be a priority A nt...

Lung cancer is the leading cause of cancer death, and approximately 15% of all lung cancer patients have small-cell lung cancer (SCLC). Although second-line chemotherapy can produce tumor regression, the prognosis is poor. Amrubicin hydrochloride (AMR) is a synthetic anthracycline anticancer agent and a potent topoisomerase II inhibitor. Here, we discuss the features of SCLC, the chemistry, pha...