Bioactive polymeric materials based on calcium phosphates have tremendous appeal for hard tissue repair because of their well-documented biocompatibility. Amorphous calcium phosphate (ACP)-based ones additionally protect against unwanted demineralization and actively support regeneration of hard tissue minerals. Our group has been investigating the structure/composition/property relationships o...

Maryam Nabiyouni, Sarit B Bhaduri. University of Toledo, Toledo, OH 43606 Statement of Purpose: Nonviral gene delivery has gained much attention due to its potential in addressing the viral gene delivery limitations like unintentional mutagenesis. Different natural and synthetic materials such as polymers, lipids, and calcium phosphate particles have been developed as DNA carriers. However, the...

A plasma- and precursor-assisted biomimetic process utilizing plasma and alternate dipping treatments was applied to a Leed-Keio artificial ligament to produce a thin coating of apatite in a supersaturated calcium phosphate solution. Following plasma surface modification, the specimen was alternately dipped in calcium and phosphate ion solutions three times (alternate dipping treatment) to crea...

Introduction: Nowadays, several casein components such as casein phosphopeptide amorphous calcium phosphate (CPP-ACP) are vastly considered as a suitable replacement for fluoride component . The aim of this study was to compare the effect of CPP-ACP paste and fluoride varnish on dentin hypersensitivity reduction. Materials & Methods: In this clinical trial study, thirty adult patients betwee...

This study aimed to investigate the free calcium released from different brands of toothpaste after incorporation with a beta-tricalcium phosphate (?-TCP)/amorphous (ACP) mixed powder and ?-TCP alone. Four were used for experiment: Nano-Bio Activation Toothpaste, Colgate Total Advanced Whitening BORONIA Herbal Whitening, BioMin F. The investigated ACP powders prepared by two-step sintering meth...

Generally, a solution nucleation model is used to study biomineralization kinetics. However, we found that the amorphous calcium phosphate (ACP)-mediated hydroxyapatite (HAP) nucleation in simulated body fluids (SBF) had a different profile from the linear relationship between ln J and ln(-2) S (J, nucleation rate; S, supersaturation). This behaviour was alternatively explained by a developed h...

In this paper, yolk-shell hollow nanospheres of amorphous calcium phosphate (ACP) are prepared, and its loading capacity is investigated by comparing with that of solid-shell hollow structure ACP and cage-shell hollow structure ACP. Results show that the products are yolk @ cage-shell of ACP with large shell's pores size (15-40 nm) and large cavity volume. Adsorption results show that the loadi...