نتایج جستجو برای: aminopeptidase n

تعداد نتایج: 978986  

ژورنال: دانشور پزشکی 2013
جلائی پور, شهره , جلیلوند, فروزنده , حاجی حسینی, رضا , دوست‌خواه, نرگس , صراف‌نژاد, عبدالفتاح , کبودانیان اردستانی, سوسن ,

 Background and Objective: Aminopeptidases remove the amino acids from the N-terminal of proteins and peptides. Aminopeptidase N (CD13) and leucine aminopeptidase are involved in processing and presentation of pathogens to immune cells. Also, enzyme activity in some viral infection and tumors are high. In this study, the activity of CD13 in serum with high level of brucella antibody wa...

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Journal: :Anticancer research 2012
María Dolores Mayas María Jesús Ramírez-Expósito María Pilar Carrera Manuela Cobo José Manuel Martínez-Martos

BACKGROUND Angiotensin peptides play roles in brain tumor infiltration and associated angiogenesis. MATERIALS AND METHODS We explored the roles of soluble and membrane-bound forms of renin-angiotensin system-regulating aminopeptidase N (APN)-, aminopeptidase B (APB)-, glutamate aminopeptidase- and aspartate aminopeptidase (AspAP)-specific activities on tumor growth in the rat C6 glioma model ...

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2012
Brandon A. Kemp John F. Bell Daniele M. Rottkamp Nancy L. Howell Weijian Shao L. Gabriel Navar Shetal H. Padia Robert M. Carey

In angiotensin type 1 receptor–blocked rats, renal interstitial (RI) administration of des-aspartyl-angiotensin II (Ang III) but not angiotensin II induces natriuresis via activation of angiotensin type 2 receptors. In the present study, renal function was documented during systemic angiotensin type 1 receptor blockade with candesartan in Sprague-Dawley rats receiving unilateral RI infusion of ...

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IL-4 up-regulates various monocytic properties that are associated with pro-inflammatory functions. Paradoxically, IL-4 may also act as an anti-inflammatory agent by down-regulating the production of several inflammatory mediators. As the activity of some mediators has recently been shown to be regulated by peptidases, we examined whether IL-4 was able to modulate the expression of a cell membr...

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Journal: :Hypertension 2012
Brandon A Kemp John F Bell Daniele M Rottkamp Nancy L Howell Weijian Shao L Gabriel Navar Shetal H Padia Robert M Carey

In angiotensin type 1 receptor-blocked rats, renal interstitial (RI) administration of des-aspartyl(1)-angiotensin II (Ang III) but not angiotensin II induces natriuresis via activation of angiotensin type 2 receptors. In the present study, renal function was documented during systemic angiotensin type 1 receptor blockade with candesartan in Sprague-Dawley rats receiving unilateral RI infusion ...

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Journal: :acta medica iranica 0
m. r. nikoobakht g. pourmand a. amidi h. hashemi a. r. abedi

biological effects extracorporeal shock wave lithotripsy (eswl) is not precisely known. we have evaluated two urinary enzymes activity n-acetyl-b-d-glucosamine (nag) and alanine amino peptidase (aap) before and after unilateral eswl as markers for renal parenchymal damage. forty eight patients with kidney stones (mean age 39) who had presented for the first time or at least one year after their...

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