D M U R'NCO + RNH, ^ R ‘N = C —CT 2> R'NHCONHR (1) I + NH, I R 1 rearrangement. Subsequent work has shown that this type of mechanism is not, in fact, satisfactory for alcoholysis, and that a mechanism in which nucleophilic attack and proton transfer are concerted, and involve associated nucleophile, is likely [3, 4, 5]. Such a mechanism [equation (2) —(3)] also provides a better explanation of...

Here, in situ synthesis of nano zinc oxide, along with aminolysis of polyester fabric, has simultaneously been carried out by using triethanol amine (TEA) and zinc acetate. The ZnO nano particles (NPs) were formed and stabilized on the fabric surface by amine compound at 130 °C for 1 h. The synthesis of nano ZnO particles on the polyester fabric were confirmed by X-ray diffraction (XRD) pattern...

The carbonation of biosourced 1,2-diols is a sustainable avenue for the synthesis bis-five-membered cyclic carbonates (bis-5CCs), precursors valuable class polymers, example, polyhydroxyurethanes (PHUs). In this work, we performed direct optically pure sugar-based butadiene tetraols, namely, (i) meso-erythritol and (ii) its (S,S) diastereoisomer, (L)-threitol. corresponding vicinal bis-5CCs, er...

A comprehensive computational mechanistic study regarding intramolecular hydroamination (HA) of aminoalkenes mediated by a recently reported class of highly active cyclopentadienyl-bis(oxazolinyl)borate {Cpo}Y(III) alkyl compounds is presented. Two distinct mechanistic pathways of catalytic HA mediated by rare earth and alkaline earth compounds have emerged over the years, describing amidoalken...

A kinetic study on aminolysis of 4-chloro-2-nitrophenyl X-substituted-benzoates (6a-i) in MeCN is reported. The Hammett plot for the reactions of 6a-i with piperidine consists of two intersecting straight lines, while the Yukawa-Tsuno plot exhibits an excellent linear correlation with ρX = 1.03 and r = 0.78. The nonlinear Hammett plot is not due to a change in rate-determining step (RDS) but is...

We have presented a near-infrared fluorescent probe Lyso-JN for the detection of nitroxyl (HNO) in cells and in vivo. Lyso-JN is comprised of three moieties: an Aza-BODIPY fluorophore, a HNO-response modulator, diphenylphosphino-benzoyl, and a lysosomal locator, alkylmorpholine. The detection mechanism is based on aza-ylide intramolecular ester aminolysis reaction with HNO. The probe holds the ...

synthetase-like enzyme. Carboxypeptidase Y (CPY, EC 3.4.16,5) is a yeast vacuolar carboxypeptidase that catalyzes the removal of the C-terminal amino acid from peptides.3) In addition, CPY has aminolytic activity by replacing C-terminal amino acid of the peptide with a free amino acid,4'S) Therefore, CPY seems to participate in the turnover and proteolytic processing of proteins.6) Both hydroly...