securigera securidaca (l.) degen & dorfl grows in different parts of iran. the seeds of the species are used in iranian folk medicine as an anti-diabetic agent. many studies have established hypoglycemic effects of amino acids and in the present investigation, amino acids of securigera securidaca seeds have been evaluated. the ground seeds were extracted using petroleum ether, hot ethanol a...

conclusions the distribution of amino acid mutations as well as the ratio between missense and silent nucleotide mutations (dn/ds) showed that a narrowly focused immune pressure had already been on the surface protein (especially ctl epitopes) which led to the emergence of escape mutants in these patients who were in tolerance phase of chronicity. materials and methods the surface genes from 17...

castor bean, peanut, soy bean and safflower protein isolates were prepared. the amino acid content of each of the protein isolates was analysed and the essential amino acid contents were compared with the fao human requirements. the results indicated that castor bean has the highest oil and the protein content of defatted meal. safflower 3148 (marand, iran) has the highest amount of essential a...

background: hypertension is considered an independent risk factor for cardiovascular mortality in diabetic patients. the present study was designed to determine the role of gamma amino butyric acid b (gabab) receptor and l-arginine (l-arg) in gaba-induced vasorelaxation in normal and streptozotocin-induced diabetic rat vessels. methods: diabetes was induced by a single i.p. injection of strepto...

to study the anticoccidial and antioxidant effects of garlic powder (gp) and total sulfur amino acid (tsaa) on growth performance, faecal oocyst output, oxidative stress indicators and antioxidant status markers in broiler chickens, a 2 × 2 × 2 splitplot-factorial arrangement of treatments was used. a total of 480-day-old male broiler chickens were equally assigned to two plots. two hundred for...

in this study, the cdna growth hormone (cgh) of the belugasturgeon (husohuso) and russian sturgeon (acipensergueldenstaedtii) were cloned and sequenced, and phylogenetic relationships were examined using nucleic acid and amino acid sequences. the nucleotide sequence of the beluga gh has an open reading frame of 645 nucleotides encoding a protein 214 amino acid residues. the signal peptide cleav...

A human pancreas-specific protein (PASP), previously characterized as a serum marker for acute pancreatitis and pancreatic graft rejection, has been identified as pancreatic procarboxypeptidase B (PCPB). cDNAs encoding PASP/PCPB were isolated from a human pancreas cDNA library using a combination of nucleic acid hybridization screening and immunoscreening with antisera raised against native PAS...

Little is known about how water stress including drought and flooding modifies the ability of plants to resist simultaneous attack by insect feeding and transmission of insect-vectored pathogen. We analyzed insect population growth, feeding behaviors, virus transmission, and plant amino acid profiles and defense gene expression to characterize mechanisms underlying the interaction between water...

The isolation of auxotrophic mutants, which is a prerequisite for a substantial genetic analysis and metabolic engineering of obligate methylotrophs, remains a rather complicated task. We describe a novel method of constructing mutants of the bacterium Methylophilus methylotrophus AS1 that are auxotrophic for aromatic amino acids. The procedure begins with the Mu-driven integration of the Esche...

abstract           introduction: genetic variations in the gene encoding endothelial nitric oxide synthase (enos) enzyme affect the susceptibility to cardiovascular disease. identification of the way these changes affect enos structure and function in laboratory conditions is difficult and time-consuming. thus, it seems essential to perform bioinformatics studies prior to laboratory studies to ...