Ameloblastic fibroma (AF) is an uncommon mixed neoplasm of odontogenic origin frequently seen in the second decade of life. It mainly presents as an intrabony lesion but can even occur peripherally. Histologically, our case showed hypercellular areas, an uncommon feature seen in typical AF. Whether this benign lesion is treated by mode of enucleation and curettage or by extensive surgery is sti...

Ameloblastic fibroma (AF) is a benign tumor, it is a true mixed tumor composed of neoplastic epithelium and mesenchymal. This tumor is rare, and it almost arises in the mandible. A 22-years old female patient referred AF in the maxillary was present. The tumor was asymptomatic, except the right facial bulge. The radiograph showed a well-circumscribed neoplasm with several low density cysts invo...

Cell proliferation assays are performed using antibodies against nuclear proteins associated with DNA replication. These nuclear proteins have gained special interest to predict the biological and clinical behaviors of various tumors. The aim of this study was to analyze the presence of Ki-67 protein and the minichromosome maintenance-2 (MCM2) and maintenance-3 (MCM3) proteins in ameloblastoma....

The first description of the rare odontogenic tumor, ameloblastic fibrosarcoma (AFS), was in 1887 [1]. Various terminologies like ameloblastic dentinosarcoma and ameloblastic odontosarcoma were employed in the past to denote these types of lesions, which depended upon the presence of enamel or dentin. In the recent past, multiple authors considered these lesions to be the histological variants ...

the ameloblastic carcinoma is a rare malignant counterpart of the ameloblastoma. ameloblastic carcinoma is a malignant lesion with characteristic histologic features and behavior that dictates a more aggressive surgical approach than that of a simple ameloblastoma. however, reliable evidence of its biologic activity is currently unavailable due to the scarcity of well-documented cases. we prese...

The usual treatment for ameloblastic carcinoma is surgical resection. effectiveness of radiotherapy and chemotherapy the disease has not been determined, few effective treatments are available local recurrence distant metastasis. Recently, molecular targeting using BRAFV600E inhibitors attracted interest as a ameloblastoma carcinoma.