BACKGROUND Wound healing is widely discussed in the medical literature. This study compared the healing effect of aloe vera extract and silver sulfadiazine in burn injuries in experimental rat model. METHODS Sixteen rats were randomly assigned to one of two groups, each group 8 rats. A deep second-degree burn on the lower back and 3(rd) degree burn on upper back of each rat were created with ...

Aloe emodin is isolated compound of aloe vera which is used traditionally as an anti-inflammatory agent. In vitro pharmacokinetic data suggest that glucuronosyl or sulfated forms of aloe emodin may provide some limitations in its absorption capacity. Aloe emodin was reported to have in vitro anti-inflammatory activity due to inhibition of inducible nitric oxide (iNO) and prostaglandin E2, via i...

Aloe vera gel of 50% and 96.4% were tested for its wound healing activity by topical application in experimental rats. The effect of Aloe vera gel on wound healing was evaluated by wound excision model and histopathology was used to study the effect on wound healing. The effect produced by Aloe vera gel with reference to wound contraction, wound closure, decrease in surface area of wound, tissu...

BACKGROUND Due to increasing resistance to antibiotics and rising incidence of oral diseases, there is a need for alternative treatment modalities to combat oral diseases. The aim of the present study was to access the effect of Aloe vera mouthwash on the dental plaque in the experimental period of 4 days and to compare it with the bench mark control chlorhexidine and placebo (saline water). ...

Aloe vera L. (hereinafter referred to as “Aloe” or “Aloe vera”) has been used for millennia for medicinal purposes both topically and internally. Previous publications have shown a great deal of inconsistency of quality and therefore biological activity from commercially available Aloe vera products. The purpose of this study was to determine the immunomodulatory activity of an organic freeze d...

Little work is done to develop Aloe vera (AV) using probiotics. To explore the potential benefits, the antioxidant effects and the antibacterial effects on foodborne pathogens of Aloe fermentation supernatant were evaluated in vitro. Our results indicated that the Aloe fermentation supernatant fermented by Lactobacillus plantarum HM218749.1 had very strong scavenging capacities of the DPPH (86%...

Aloe vera (Asphodeloideae) is a medicinal plant in which useful secondary metabolites are plentiful. Among the representative secondary metabolites of Aloe vera are the anthraquinones including aloe emodin and chrysophanol, which are tricyclic aromatic quinones synthesized via a plant-specific type III polyketide biosynthesis pathway. However, it is not yet clear which cellular responses can in...

The purpose of this study was to evaluate the effect of topical administration of Aloe vera on excision wound healing in mice. Mechanical skin lesion were used here to assess the efficacy of Aloe vera applied topically. Macroscopic and microscopic evaluation of skin lesions was performed. Excision wounds were made on the back of albino mice. Albino mice were divided into following groups, as co...

In ayurveda, a tradional system of medicine, aloe vera (Aloe Barbadensis) is commonly used in sunburn, minor cuts, insect bites and used as wound healing, anti-inflammatory, antiviral, antitumor, laxative and in the treatment of frostbite and psoriasis. The whole plant as well as its specific parts (leaves, roots), plant extracts and its active constituent mucopolysaccharides [MPS] (long chain ...

The aim of this study was to determine effects of six weeks endurance training and Aloe Vera supplementation on COX-2 and VEGF levels in mice with breast cancer. For this purpose, 35 rats were randomly divided into 5 groups: control (healthy) and 4 cancer groups: control (cancer only), training, Aloe Vera and Aloe Vera + training. Breast cancer tumors were generated in mice by implantind. The t...