The use of natural anti-diabetic medications in treating diabetes is receiving more attention daily. This study evaluated the phytochemical constituents and properties leaves Coccinia barteri on alloxan induced diabetic rats. powdered leaf was macerated methanol for 72hrs then fractionated with ethyl acetate, chloroform aqueous solvents. Phytochemical analytical evaluations were done using stan...

The hypoglycemic effects after oral administration of vanadium have been studied previously in many species such as rats, mice and even humans. However, there has been no prior report on the glucose lowering effect of vanadium on diabetic dogs. Therefore, the purpose of this study was to evaluate the hypoglycemic effects of oral vanadium on diabetic dogs. Diabetes mellitus in the dogs studied w...

Melatonin and its metabolites have potent antioxidant/anti-inflammatory properties, they proven to be highly effective in a variety of disorders linked inflammation oxidative stress. The object this experimental research was ascertain the influence aging on level basal glycemia activities glucose-6-phosphate dehydrogenase [EC1.1.1.49], pyruvate kinase [EC 2.7.1.40] glutathione reductase [EC1.6....

The aim of this study is to evaluate the effects of soya bean supplement blood glucose levels and haematological parameters on alloxan-induced diabetes in Wistar rats. The animals were grouped into four groups of five rats in each group. Diabetes was induced by single intraperitoneal injection of Alloxan monohydrate at a dose of 150mg/kg body weight. The animals were fed with 25% and 50% of the...

Natural remedies from medicinal plants are considered to be effective and safe alternative treatment for diabetes mellitus. The aim of present study was to demonstrate the hypoglycemic and anti-diabetic activity of the Ethanolic extract of tinospora cardifolia whole plant in alloxan induced diabetic animals with a view to explore its use for the treatment of diabetes mellitus in humans. The Eth...

The effects of fibre-enriched biscuit on biomarkers associated with hepatotoxicity in diabetic rats were investigated. Diabetes was induced by single intraperitoneal injection of alloxan monohydrate. Treatment lasted for 14 days after which the rats were sacrificed by cervical dislocation. Blood serum was analyzed to determine hepatic function enzymes. The liver was also analyzed to determine h...

In this experimental study, 30 adult male Wistar rats divided into 5 groups (n=6). Experimental rats were treated with one intraperitoneal injection of 120 mg/kgbw Alloxan monohydrate alone or in combination with 28 days of oral administration with aqueous extract of Rhus coriaria (50, 100 and 250 mg/kgbw) while the control rats received normal saline. At the end of the study, blood glucose, ma...

Aims: To investigate the effects of Cucumis sativus and Prunus armeniaca juices on blood glucose, insulin electrolytes alloxan-induced Diabetic male Sprague Dawley rats.
 Study Design: An experimental study involving a total eighty (80) rats was used.
 Place Duration Study: Department Medical Laboratory Science, Rivers State University, Nigeria, between January 2021 February 2022.&#x0...

Abstract Background In diabetic animals, there is a significant increase in plasma glucose, serum total cholesterol, triglyceride, and low-density lipoprotein levels, decreased body weight, liver muscle glycogen, high-density lipoprotein. Effective treatment of diabetes mellitus not yet known, even though the management considered global concern. Plants herbs have played an important role healt...

objectives: diabetes mellitusmanifests itself in a wide variety of complications and the symptoms of this disease are multifactorial. previousstudies proved that this disease is directly related to hyperglycemia and hyperlipidemia. the aim of this study was to investigate the hypoglycemic and hypolipidemic effects of hydroalcoholic extract of prangos frulacea (l.)lindlin alloxan-induced diabeti...