During the 1994-2003 study period, patch testing was carried out in 1102 subjects (740 female and 362 male, mean age 39.8, range 7-81 years) suspected to have allergic contact dermatitis (ACD). Epicutaneous patch test with a standard series of contact allergens was made by the Institute of Immunology, Zagreb, Croatia, according to the Internationational Contact Dermatitis Research Group (ICDRG)...

Methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) is a combination preservative used in personal care and household products and is a common cause of allergic contact dermatitis (ACD). Recently, MI alone, without MCI, has been increasingly used in consumer products in attempts to minimize allergic reactions. Wet wipes are extensively tested and traditionally believed to be innocuous. M...

Acrylic nails, including sculptured nails and the new ultraviolet-curable gel polish lacquers, have been associated with allergic contact dermatitis (ACD). We report 2 cases of ACD to acrylic nails with severe onychodystrophy and psoriasiform changes including onycholysis and subungual hyperkeratosis. In both cases, the patients did not realize the association between the use of acrylate-based ...

Parabens, methyl, ethyl, propyl, benzyl, and butyl, are the most common preservatives in use today. They are the alkyl esters of p-hydroxybenzoic acid and are used extensively because they are relatively nonirritating and nontoxic and offer good antimicrobial coverage. Testing for paraben allergen can be done by patch testing. Two cases of allergic contact dermatitis (ACD) to parabens are used ...

Contact allergy (CA), a pathologic response after (usually repeated) contact to environmental substances of low molecular weight occurring in a varying proportion of exposed persons, often results in clinical disease, allergic contact dermatitis (ACD), which can be disabling. CA is diagnosed by patch testing, a technique of controlled exposure of patients suspected to have ACD to a standardized...

Allergic contact dermatitis (ACD) in children was previously considered to be a rare occurrence. However, the growing number of case reports and cross-sectional studies through the past three decades indicate that ACD is, in fact, a highly relevant diagnosis in children. Furthermore, the frequency of ACD in children seems to be increasing. In 1999, a review of the literature reported prevalence...

Immunotherapy of allergic contact dermatitis (ACD) has tantalized allergists since the beginning of the 20th century. The term immunotherapy refers to treatment of disease by either inducing/enhancing or preventing/suppressing an immune response. As contact allergy is an excessive immune reaction to otherwise harmless environmental substances (haptens), immunotherapy of ACD should be aimed at p...

The epicutaneous patch testing is regarded as the best method of diagnosis for allergic contact dermatitis (ACD). Patch tests can be used to confirm a suspected allergic contact dermatitis and either to recommend avoidance of particular products or to recommend alternative products in a particular patient. It is based upon re-exposing the skin of the patient to suspected allergens under control...

We report a case of a non-atopic, 37-year-old nail technician who developed blisters, itching, scaling, and redness, that is, allergic contact dermatitis (ACD), on the hands and fingers owing to sensitization tomethacrylates and acrylates, in this article called (meth)acrylates, only months after finishing her trainee period. The protective effect of gloves was studied in an in vivo system simu...