نتایج جستجو برای: alkylphenols

تعداد نتایج: 298  

Journal: :Journal of medicinal chemistry 2017
Linlin Qin Lei Ren Songlin Wan Guoliang Liu Xinfeng Luo Zhenhong Liu Fangqiong Li Yan Yu Jianyu Liu Yonggang Wei

A novel series of optically active 2,6-disubstituted alkylphenols with improved anesthetic profiles compared to widely used propofol were synthesized. The incorporation of the cyclopropyl group not only increased the steric effect but also introduced stereoselective effects over their anesthetic properties. Compounds 1, 2, and 6 were selected as potential candidates for further preclinical deve...

2014
Moosa Faniband Christian H Lindh Bo AG Jönsson

Endocrine-disrupting compounds are exogenous agents that interfere with the natural hormones of the body. Human biological monitoring is a powerful method for monitoring exposure to endocrine disrupting compounds. In this review, we describe human biological monitoring systems for different groups of endocrine disrupting compounds, polychlorinated biphenyls, brominated flame retardants, phthala...

Journal: :Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi) 1999

Journal: :Open Chemistry 2023

Abstract In marine ecosystems, living organisms are continuously exposed to a cocktail of anthropogenic contaminants, such as microplastics (MPs) and endocrine disrupting compounds (EDCs). Being able adsorb organic compounds, MPs would act an additional contamination vector for aquatic organisms. To support this hypothesis, the sorption six EDCs on MPs, including 4- t -butylphenol, -octylphenol...

2014
Hironori Tsuchiya Maki Mizogami

Objective: While substituted phenols have a variety of pharmacological activity, the mechanism underlying their anesthetic effects remains uncertain especially about the critical target. We characterized the lipid membrane-interacting properties of different phenols by comparing with general anesthetic propofol and local anesthetics. Based on the results, we also studied the pharmacological eff...

Journal: :Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 2002
Asako Ozaki Yukihiko Yamaguchi Akiyoshi Okamoto Nobuko Kawai

Infants, whose growth and development are highly dependent upon the endocrine system, are particularly vulnerable to endocrine disruptor exposure. In our study, we examined whether or not alkylphenols, bisphenol A, benzophenone, di(2-ethylhexyl)adipate and 10 phthalates are present in containers of baby food. Furthermore, the migration into food-simulating solvents was also examined. Sixteen ty...

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