BACKGROUND Tissue damage is associated with pain, which is an alarming sign. Aspirin and morphine have been widely used in recent decades for management of pain. Medicinal herbs have been in use for treatment of different diseases for centuries. Many of these herbs possess analgesic activity with relatively less incidences of adverse effects. The strong positive correlation of alkaloids in medi...

The overproduction of specialized metabolites requires plants to manage the inherent burdens, including the risk of self-intoxication. We present a control mechanism that stops the expression of phytoalexin biosynthetic enzymes by blocking the antecedent signal transduction cascade. Cultured cells of Eschscholzia californica (Papaveraceae) and Catharanthus roseus (Apocynaceae) overproduce benzo...

Catharanthus roseus (L.) G.Don is a plant which produces anticancer and anti-mitotic indole alkaloids. Colchicine is an anti-mitotic drug. Anti-mitotic effects of Vinca herbacea Waldst. & Kit. indole alkaloids is unknown. The study were evaluated the antimitotic effect of alkaloids of V. herbacea, Catharanthus roseus andcolchicineon mitosis and microtubule arrangement of human blood cells. In t...

Amaryllidaceae is a well-known family for its high alkaloidal content. These alkaloids comprise a unique group of bases that have been found to occur in this family. The Amaryllidaceae alkaloids represent a large and still expanding group of isoquinoline alkaloids, the majority of which are not known to occur in any other family of plants This article reports on the phytochemical investigation ...

background & aim: fabaceae plant family cow tail (smirnovia iranica) is one of the valuable species of native shrubs and sand dunes in the central region of iran which is consistent with the production of forage and soil conservation and creating a beautiful landscape; it has the active ingredients of medicinal values. the purpose of this study was to investigate the presence of some phytoc...

the diallel cross design is frequently utilized to obtain information on genetic effects, estimates of general and specific combining ability (gca and sca) and to identify promising heterotic combinations as well as heterotic patterns. in the present study, heterotic crosses were identified for specific alkaloids in opium poppy (papaver somniferum l.) following yan’s gge biplot model by use of ...

The tuber of Corydalis yanhusuo is a famous traditional Chinese medicine and found to have potent pharmacological effects, such as antinociceptive, antitumor, antibacterial, anti-inflammatory, and anti-depressive activities. Although there are several methods to be developed for the analysis and detection of the bioactive ingredients' alkaloids, so far, only few prominent alkaloids could be qua...

Objective: The present study was conducted to investigate antibacterial properties of fruit and flower of Peganum harmala. Material and Methods: Column chromatography, followed by preparative thin layer chromatography (TLC) was used for final purification. The structure of pure alkaloids was determined using spectroscopic methods (1H-N...

Two new alkaloids were isolated together with 16 known lupin alkaloids from the leaves and stems of Chinese Maackia amurensis. Their structures were determined by spectroscopic methods to be (-)-6alpha-methoxylupanine and (-)-5alpha-(12-cytisinylmethyl)-6alpha-hydroxylupan ine and identified by comparison with synthetic samples. The structures of lupin alkaloids were also related to the geograp...

Chopra and others (1927) have shown that the alkaloids of Holarrliena antidysenterica possess marked amcebicidal properties, and Ghosh and Ghosh (1928) have shown that the Indian species of H. antidysenterica contain, besides conessine, two other alkaloids which they named kurchicine and kurcliine, respectively. Ghosh and Bose (1932) isolated these alkaloids in pure form and showed that the alk...