1. In order to clarify further the phenomenon of post-obstructive diuresis, clearance and micropuncture experiments were done before and after relief of partial ureteral obstruction in rats with a solitary hydronephrotic kidney. 2. Glomerular filtration rate, urine flow and sodium excretion increased markedly, whereas surface nephron glomerular filtration rate increased only slightly and intrat...

OU RAL administration of diuretics with a safe and satisfactory diuresis has always been a therapeutic goal. Diuresis could then be accomplished at a slow but regular rate, with the avoidance of a sudden profuse diuresis,' which is very uncomfortable for the patient, and produces marked alteration of the fluid and electrolyte balance. Rapid diuresis has been known to cause attacks of gout,2 tet...

Physicians often recommend that patients with UTI increase their fluid intake. This practice has continued for years largely unchallenged because it is so logical: a water diuresis would serve to “flush” the urinary tract of infecting organisms and the increased frequency of voiding would reduce bacterial multiplication in the bladder. However, since dilution of urine affects both the osmolalit...

This study analyzes the effects of fluid resuscitation in the crush victims of the Bingol earthquake, which occurred in May 2003 in southeastern Turkey. Questionnaires asking about demographic, clinical, laboratory, and therapeutic features of 16 crush victims were filled in retrospectively. Mean duration under the rubble was 10.3 +/- 7 h, and all patients had severe rhabdomyolysis. Fourteen pa...

OU RAL administration of diuretics with a safe and satisfactory diuresis has always been a therapeutic goal. Diuresis could then be accomplished at a slow but regular rate, with the avoidance of a sudden profuse diuresis,' which is very uncomfortable for the patient, and produces marked alteration of the fluid and electrolyte balance. Rapid diuresis has been known to cause attacks of gout,2 tet...

UNLABELLED Metabolic acidosis slowly develops during renal impairment natural evolution towards ESRD and represents an important contributing factor of CKD progression. Although, several clinical and experimental trials reported the major impact of metabolic acidosis on CKD evolution, the pathophysiology mechanism remains a matter of debate. Furthermore, international guidelines do not impose a...