The agent responsible for prion diseases is a misfolded form of a normal protein (PrPC). The prion hypothesis stipulates that PrPC must be present for the disease to manifest. Cervid populations across the world are infected with chronic wasting disease, a horizontally-transmissible prion disease that is likely spread via oral exposure to infectious prions (PrPCWD). Though PrPCWD has been ident...

Duplication of the gastrointestinal tract occur any part alimentary from tongue to anus. Male have slightly more predominance than females. Gastrointestinal duplication will a varied presentation. Ileum and oesophagus are most commonly involved. Colonic is rare can present with diagnostic difficulties. has presence well developed coat smooth muscle, intimately attached in mesentric region show ...

Duplication of the alimentary tract is uncommon but duplication of the appendix is rare. Basu et al. (1959), in reporting 28 cases of duplication of the alimentary tract, had no case of appendix duplex. Picoli ( 1892) reported the first case of apendix duplex in a female patient who had associated anomalies of duplication of the entire large bowel, two uteri with two vaginae, ectopia vesicae an...

Anorectal malformation (ARM) is one of the most common congenital anomaly that requires emergency surgery in the neonatal period. ARMs are frequently associated with other life threatening congenital anomalies. Commonly associated anomalies are genito-urinary, cardiovascular, gastro-intestinal, skeletal and spinal. Alimentary tract anomalies are frequently masked by the intestinal obstruction p...