The reversible, temperature-dependent change in the permeability of a phospholipid bilayer has been used for controlling the diffusion rate of encapsulated molecular payload from liposomes. Liposomes were preloaded with a fluorescent dye and immobilized in calcium alginate hydrogel microparticles that also contained iron oxide nanoparticles. The composite microparticles were produced by a drop-...

Abstract Brown seaweed Sargassum latifolium produces a sufficient amount of alginate. It is derived from the cell wall as natural anionic polysaccharide. In present study, alginate was extracted S. , its physicochemical properties, potential for silver nanoparticles formation, characterization nanoparticles, and antibacterial activity studied. Physical analysis sodium colour (pale yellow), yiel...

It has been found that the adsorption of antigens onto chitosan particles is an easy and unique mild loading process suitable to be used with vaccines. In order to increase the stability of this particles and to prevent an immediate desorption in gastrointestinal fluids, a coating process with sodium alginate was developed. One of the challenges of this developing process was to keep the partic...

The aim of this study was to prepare surfactant free Diclofenac sodium loaded ethyl cellulose nanoparticles by O/W single emulsion solvent evaporation high pressure homogenization technique.In the preparation of O/W single emulsion sodium alginate used as an emulsifying/stabilizing agent. Microparticles of nine different batches at different condition were prepared after that optimized batch wa...

The aim of this study was to evaluate the antibacterial effect of nisin-loaded chitosan/alginate nanoparticles as a novel antibacterial delivery vehicle. The nisin-loaded nanoparticles were prepared using colloidal dispersion of the chitosan/alginate polymers in the presence of nisin. After the preparation of the nisin-loaded nanoparticles, their physicochemical properties such as size, shape, ...

Advances in nanotechnology have demonstrated potential application of nanoparticles (NPs) for effective and targeted drug delivery. Here we investigated the antimicrobial and immunological properties and the feasibility of using NPs to deliver antimicrobial agents to treat a cutaneous pathogen. NPs synthesized with chitosan and alginate demonstrated a direct antimicrobial activity in vitro agai...

Nanoporous polyurea-cross-linked Ca-alginate (X-Ca-alginate) aerogels were prepared by reacting an aliphatic or aromatic triisocyanate with the preformed biopolymer network post gelation and drying in supercritical CO2. The nanomorphology of native together those different X-Ca-alginate investigated using low-voltage scanning electron microscopy, N2-sorption porosimetry, contrast variation smal...

BACKGROUND Current anti-cancer drug therapy results in systemic side effects due to non-specific uptake by normal healthy noncancerous tissues. To alleviate this difficulty, many attempts have been devoted to the development of new delivery systems such as polymeric Nanoparticles (NPs). In this study, we prepared ICD-85 NPs based on sodium alginate and analyzed the cytotoxic activity of ICD-85 ...

Intestinal organoids can be used as an ex vivo epithelial model to study different drug delivery effects on cells’ luminal surface. In this study, the impact of surface charge 5-ASA loaded PLGA nanoparticles into lumen was investigated. Alginate and chitosan were coat provide negative positive charges particles, respectively. The organoid growth viability not affected by presence either alginat...

The objective of this work was to characterize the cinnamon oil nanocapsule that contained alginate-chitosan as coating agents. In this work, cinamonn oil loaded chitosan nanoparticles (CS-alginate NP-cinamonn) are prepared by a two-step process including oil/water emulsion and ionic gelation. In this study, cinamon as a core material was nanoencapsulated with chitosan alginate at a ratio of 1:...