This paper is concerned with the airway closure problem and investigates the quasi-steady deformation characteristics of strongly collapsed (buckled) airways occluded by liquid bridges of high surface tension. The airway wall is modeled as a thin-walled elastic shell, which deforms in response to an external pressure and to the compression due to the surface tension of the liquid bridge. The go...

Studying airflow characteristics in the human respiratory system is important for understanding properties of aerosol transport and deposition. This study first constructed a whole-lung airway model (WLAM) with random features extending from mouth to 13th generation bronchus. The large eddy simulation method utilized investigate both averaged fields flow unsteadiness under inspiratory rates 15 ...

background: it has been shown that inhalation of carbonaceous particulate matter may impair lung function in children. objective: using the carbon content of airway macrophages as a marker of individual exposure to particulate matter derived from fossil fuel, we sought direct evidence for this association. methods: 300 children from puffed rice industrial areas and 300 children from population ...

Recent studies have implicated keratin 5 (KRT5)+ cells in repopulation of damaged lung tissue following severe H1N1 influenza virus infection. However, the origins of the cells repopulating the injured alveolar region remain controversial. We sought to determine the cellular dynamics of lung repair following influenza infection and define whether nascent KRT5+ cells repopulating alveolar epithe...

BACKGROUND Airway responsiveness and inflammation are associated with the clinical manifestations of asthma and the response to pharmacological therapy. OBJECTIVE To investigate if airway responsiveness and inflammatory characteristics are related to asthma exacerbations during pregnancy. MATERIALS AND METHODS In women with asthma who were prescribed controller medication and monitored clos...

Model studies incorporating known morphological properties of the airways predict different narrowing characteristics between large and small bronchi. However, the flow-response characteristics of airways from different regions in the bronchial tree are still unknown. We compared the responsiveness of large and small bore bronchi of the pig to luminal or adventitial stimulation by acetylcholine...

airway remodelling is characterized by the thickening and reorganization of the airways seen in mustard  lung patients. mustard lung is the  general description  for  the  chronic obstructive  pulmonary  disease induced  by  sulfur  mustard(sm). pulmonary  disease was diagnosed as the most important  disorder in individuals that had been exposed to sulfur mustard. sulfur mustard is a chemical w...

Ithough asthma is a disease that has been described for centuries, attempts at definition and criteria for diagnosis have only occurred within the last several decades. ‘There is, however, still not a universally agreed upon definition. A definition of asthma recently proposed by the expert panel on the management of asthma would probably be acceptable to most:’ “Asthma is a lung disease with t...

Aims. The aim of the study was to compare endotracheal intubation with i-gel and LMA (laryngeal mask airway) supreme supraglottic airway devices in orbital osteosynthesis surgery. Methods. 134 patients undergoing orbital plasty after fracture were enrolled in our study and were randomized into three groups: 43 in the endotracheal intubation group, 42 in the LMA-Supreme group, and 49 patients w...