1Department of Mathematical Sciences, College of Science, UAE University, 15551, Al-Ain, UAE 2Department of Physics, College of Science, UAE University, 15551, Al-Ain, UAE 3Zayed bin Sultan Al Nahyan Center for Health Sciences, College of Medicine and Health Sciences, UAE University, Al-Ain, UAE 4Department of Mathematics, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt 5Departm...

Drug-induced acute interstitial nephritis (AIN) represents a growing cause of renal failure in current medical practice. While antimicrobials and non-steroidal anti-inflammatory drugs are typically associated with drug-induced AIN, few reports have been made on the involvement of other analgesics. We report our experience in managing a 17-year-old female with AIN and subsequent renal injury fol...

BACKGROUND Gallium-67 scintigraphy has been suggested as a noninvasive method to diagnose acute interstitial nephritis (AIN). However, its diagnostic performance and usefulness remain controversial. METHODS We retrospectively reviewed the charts of 76 patients who underwent gallium-67 scintigraphy for a suspicion of AIN. Patients were classified based on kidney biopsy and/or clinical probabil...

Institute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo Egypt, Departments of Geriatrics and Gerontology, Neurology and Psychiatry, Faculty of Medicine, Ain Shams University, Cairo Egypt, Division Mental Health and Wellbeing, Medical School , University of Warwick, Coventry UK, Mental Health Division, Black Country Partnership NHS Foundation Trust, Sandwell UK and Department o...

Neurotransmitter:sodium symporters (NSSs) terminate neurotransmission by Na(+)-dependent reuptake of released neurotransmitters. Previous studies suggested that Na(+)-binding reconfigures dynamically coupled structural elements in an allosteric interaction network (AIN) responsible for function-related conformational changes, but the intramolecular pathway of this mechanism has remained unchart...

Background Tertiary lymphoid structures (TLSs) have been previously associated with ICI induced response in patients cancer, but a commensurate observation has not made immune related adverse events (irAEs). Acute interstitial nephritis (AIN) is the predominant lesion reported renal irAEs, various etiologies can also trigger development of AIN including non-ICI drugs (e.g. non-steroidal anti-in...

BACKGROUND AND AIMS Daily nutrient intake and growth of male Sprague-Dawley (SD) rats fed compositionally different diets were monitored over 114 weeks to determine whether rats fed ad libitum (AL) or diet restricted (DR) followed normal growth parameters. A second objective was to evaluate the usefulness of the American Institutes of Nutrition's AIN-93M (maintenance formulation) diet for aging...

We present surface properties of buffer films (AIN and GaN) and Al0.3Gao.zN/Al2O3-High Electron Mobility Transistor (HEMT) structures with/without AIN interlayer grown on High Temperature (HT)-AIN buffer/Al2O3 substrate and Al2O3 substrate. We have found that the GaN surface morphology is step-flow in character and the density of dislocations was about 10(8)-10(9) cm(-2). The AFM measurements a...

Acute interstitial nephritis (AIN) is characterized by inflammation of the renal interstitium and usually occurs in a temporal relationship with the medication. We present a case of an Asian male who had nephrotic range proteinuria and presented with acute kidney injury. The patient reported an acute change in physical appearance and symptomatology after the ingestion of a single dose of silden...

Acute interstitial nephritis (AIN) is an important cause of acute kidney injury that has experienced significant epidemiological and clinical changes in the last years. The classical presentation, mostly induced by antibiotics and accompanied by evident hypersensitivity manifestations (skin rash, eosinophilia, fever) has been largely replaced by oligosymptomatic presentations that require a hig...