نتایج جستجو برای: ahf pef acute heart failure preserved ef

تعداد نتایج: 1094243  

Journal: :European heart journal 2014
Michele Senni Walter J Paulus Antonello Gavazzi Alan G Fraser Javier Díez Scott D Solomon Otto A Smiseth Marco Guazzi Carolyn S P Lam Aldo P Maggioni Carsten Tschöpe Marco Metra Scott L Hummel Frank Edelmann Giuseppe Ambrosio Andrew J Stewart Coats Gerasimos S Filippatos Mihai Gheorghiade Stefan D Anker Daniel Levy Marc A Pfeffer Wendy Gattis Stough Burkert M Pieske

The management of heart failure with reduced ejection fraction (HF-REF) has improved significantly over the last two decades. In contrast, little or no progress has been made in identifying evidence-based, effective treatments for heart failure with preserved ejection fraction (HF-PEF). Despite the high prevalence, mortality, and cost of HF-PEF, large phase III international clinical trials inv...

2017
Loukas Pappas Gerasimos Filippatos

Acute heart failure (AHF) has been defined as new-onset or worsening heart failure (HF) signs and symptoms requiring urgent therapy. AHF is a leading cause of morbidity and mortality. Despite the considerable variation of clinical profiles and the substantial heterogeneity of underlying causes, the vast majority of patients with AHF present with symptoms and signs of pulmonary and systemic cong...

Journal: :Journal of the American College of Cardiology 2013
Peter van der Meer Douwe Postmus Piotr Ponikowski John G Cleland Christopher M O'Connor Gad Cotter Marco Metra Beth A Davison Michael M Givertz George A Mansoor John R Teerlink Barry M Massie Hans L Hillege Adriaan A Voors

OBJECTIVES The study sought to investigate the clinical correlates and prognostic role of anemia and changes in hemoglobin in patients hospitalized for acute decompensated heart failure (AHF). BACKGROUND Anemia is related to a poor outcome in patients with heart failure. In addition, an increase in hemoglobin during hospitalization might be a sign of effective decongestion and therefore relat...

Journal: :Journal of the American College of Cardiology 2010
Alan Maisel Christian Mueller Richard Nowak W Frank Peacock Judd W Landsberg Piotr Ponikowski Martin Mockel Christopher Hogan Alan H B Wu Mark Richards Paul Clopton Gerasimos S Filippatos Salvatore Di Somma Inder Anand Leong Ng Lori B Daniels Sean-Xavier Neath Robert Christenson Mihael Potocki James McCord Garret Terracciano Dimitrios Kremastinos Oliver Hartmann Stephan von Haehling Andreas Bergmann Nils G Morgenthaler Stefan D Anker

OBJECTIVES Our purpose was to assess the diagnostic utility of mid-regional pro-atrial natriuretic peptide (MR-proANP) for the diagnosis of acute heart failure (AHF) and the prognostic value of mid-regional pro-adrenomedullin (MR-proADM) in patients with AHF. BACKGROUND There are some caveats and limitations to natriuretic peptide testing in the acute dyspneic patient. METHODS The BACH (Bio...

2015
Andrew H. Coles

The signatures of the Master Thesis Committee signify completion and approval as to style and content of the Thesis The signature of the Dean of the Graduate School of Biomedical Sciences signifies that the student has met all master's degree graduation requirements of the school. Dedication and Acknowledgements 1 Summary 2 List of Tables and Figures 3 Preface 4 CHAPTER 1 – INTRODUCTION 5 1.1 F...

Journal: :Circulation. Heart failure 2013
Luigi Tavazzi Michele Senni Marco Metra Marco Gorini Giuseppe Cacciatore Alessandra Chinaglia Andrea Di Lenarda Andrea Mortara Fabrizio Oliva Aldo P Maggioni

BACKGROUND Clinical observational studies on heart failure (HF) deal mostly with hospitalized patients, few with chronic outpatients, all with no or limited longitudinal observation. METHODS AND RESULTS This is a multicenter, nationwide, prospective observational trial on a population of 5610 patients, 1855 hospitalized for acute HF (AHF) and 3755 outpatients with chronic HF (CHF), followed u...

Journal: :Circulation 2012
Benjamin A Steinberg Xin Zhao Paul A Heidenreich Eric D Peterson Deepak L Bhatt Christopher P Cannon Adrian F Hernandez Gregg C Fonarow

BACKGROUND Heart failure with preserved ejection fraction (EF) is a common syndrome, but trends in treatments and outcomes are lacking. METHODS AND RESULTS We analyzed data from 275 hospitals in Get With the Guidelines-Heart Failure from January 2005 to October 2010. Patients were stratified by EF as reduced EF (EF <40% [HF-reduced EF]), borderline EF (40%≤EF<50% [HF-borderline EF]), or prese...

2015
Ricardo Wage Hitesh Patel Gillian C Smith Jennifer Keegan Peter Gatehouse Vassilis Vassiliou Ee Ling Heng Carl Hayward Stuart D Rosen Alexander Lyon Raad Mohiaddin Sanjay K Prasad Dudley J Pennell Carlo Di Mario

Background Heart failure with preserved ejection fraction (HF-PEF) is common and has a poor prognosis with a 3 year mortality rate of 23%. There are currently no effective therapies for this condition. HF-PEF is characterized by symptoms of heart failure, normal or a mildly impaired ejection fraction and evidence of adverse cardiac and vascular remodelling. A feature of all heart failure is a h...

2017
Shunsuke Kiuchi Hiroto Aikawa Shinji Hisatake Takayuki Kabuki Takashi Oka Shintaro Dobashi Takahiro Fujii Takanori Ikeda

BACKGROUND Patients with acute heart failure (HF) complicated by supraventricular tachyarrhythmia (SVT) often receive continuous intravenous infusion of landiolol or diltiazem for rate control. It is unclear whether the interval from initiation of infusion to commencement of oral beta-blocker (BB) therapy differs for these two drugs. METHODS From January 2013 to July 2015, 94 consecutive pati...

2015
Masaaki Konishi Eiichi Akiyama Hiroyuki Suzuki Noriaki Iwahashi Nobuhiko Maejima Kengo Tsukahara Kiyoshi Hibi Masami Kosuge Toshiaki Ebina Kentaro Sakamaki Yasushi Matsuzawa Mitsuaki Endo Satoshi Umemura Kazuo Kimura

AIMS Non-invasive positive pressure ventilation rapidly improves the symptoms of acute heart failure (AHF). A portion of patients, however, are forced to be intubated even though intubation is associated with serious complications, and hypercapnia is often observed in AHF requiring intubation. The purpose of this study is to examine the clinical profile and management of hypercapnia in AHF pati...

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