Ewing sarcoma, including classical Ewing sarcoma of the bone and primitive neuroectodermal tumors arising in bone or extraosseous primary sites, is a highly aggressive childhood neoplasm. We present two cases of Ewing sarcoma arising from the vagina in young girls. Previously reported cases in literature focused on their pathologic rather than radiographic features. We describe the spectrum of ...

While patients with localized osteosarcoma have excellent survival rates, the prognosis for those with advanced disease is significantly worse despite aggressive multimodality therapies [1]. To overcome these limitations novel treatments are needed, especially for children and young adults with metastatic and/or recurrent osteosarcoma, whose poor rates of survival have remained relatively uncha...

Pineoblastomas are rare, malignant, pineal region lesions that account for <0.1% of all intracranial tumors and can metastasize along the neuroaxis. Pineoblastomas are more common in children than in adults and adults account for <10% of patients. The management of pinealoblastoma is multimodality approach, surgery followed with radiation and chemotherapy. In view of aggressive nature few centr...

The outcomes and management of colorectal liver metastasis have undergone many changes. The incidence of recurrence after liver resection for hepatic metastasis remains very high. Liver resection, which provides the only curative treatment, is believed to have improved the long-term outcome of these patients. However, the management and outcomes of patients with colorectal liver metastasis have...

Sebaceous gland carcinoma (SGC) of ocular adnexa is a highly malignant, multifocal in origin seen in elderly. SGCs are known to have highly virulent course of progression with more tendency to metastasize locally and systemically resulting in poor outcome. We managed a case of SGC in 55 years old with multimodality treatment consisting of surgical excision, chemotherapy for tumor bulk reduction...

basal cell carcinoma (bcc) is currently the most common cutaneous cancer found in humans. although it generally shows a relatively benign course (bccl), some cases show aggressive behavior (bcc2). until recently, traditional histologic diagnostic criteria have failed to discriminate unequivocally between bcc 1 and bcc2. in this study we selected 50 cases of bcc and categorized them into two gro...

Gastric neuroendocrine tumour (GNET), also known as carcinoids, are a very rare cause of gastric outlet obstruction and arise from entero-chromaffin like cells the mucosa. They account for 0.2/1000001 population 8.7% all Gastrointestinal carcinoids. four types based on degree differentiation, cell origin other pathologic features. Type 4 GNET referred to carcinoma accounting &lt;1% GNET. aggres...

Abstract Background Cardiac angiosarcoma is an exceptionally rare primary malignant tumour with aggressive course and typically poor prognosis. Diagnosis difficult, patients often present metastatic disease. We report the case of a patient cardiac who presents constrictive physiology due to encasement. Case summary A 65-year-old female past medical history Hodgkin’s lymphoma limited scleroderma...

BACKGROUND Anaplastic thyroid carcinoma (ATC) is a rare, aggressive malignancy with a median survival of five months. Multimodality treatment is associated with some improvement in survival, but patients are only infrequently curable. Although β-hCG secretion has been reported in many neoplasms, it has never been described in ATC. The objectives of this study were to report a case of β-hCG-secr...

background: ewing sarcoma family of tumors (esfts) is the second most common primary tumors of bone in childhood. the decision regarding the optimal modality for achieving local tumor control remains uncertain. the aim of this study was to report the clinical features and outcome as well as reviewing risk factors in patients. materials and methods: this retrospective study included 75 esfts pat...