Placebo is the second-best remedy in Homoeopathy. In day-to-day practice certain situation arise which lead us to prescribe placebo. Beginning from case taking when patient some medicines, end of treatment homoeopathic aggravation occurs, all that time physician requires middle process placebo needed during aggravation, improvement case. Certain disease conditions like Artificial Chronic Diseas...

The role of nitric oxide synthase (NOS) isozymes in the aggravation of indomethacin-induced gastric damage in adjuvant arthritic rats was investigated. Two weeks after injection of Freund's complete adjuvant, the animals were given indomethacin, and the stomach was examined for damage 4 h later. Indomethacin caused hemorrhagic lesions in the normal rat stomach, and these lesions were markedly a...

Carbamazepine (CBZ) aggravates many generalized seizures types, particularly absence seizures, but the mechanisms underlying this are poorly understood. GABA signaling within the reticular nucleus (Rt) and the ventrobasal complex (VB) of the thalamus is critical to the neurophysiology of absence seizures. The hypothesis that CBZ aggravates absence seizures by acting at the VB thalamus via a GAB...

BACKGROUNDS There have been neither appropriate guidelines nor clinical studies about the use of antithrombotics after hemorrhagic transformation (HT). We sought to find whether the use of antithrombotics after hemorrhagic infarction might be associated with aggravation of HT and neurological deterioration. METHODS This retrospective study included prospectively registered consecutive patient...

Patients with COVID-19 who have underwentsurgery high rates of mortality and complications includingincreasedrespiratorydistress, bacterialinfections, pneumothorax multi-visceralfailure. Pneumomedistinis a rare complication. Surgical indications in patients shouldbediscussed multidisciplinary consultation meeting, considering the presenceof comorbidities availability therapeutic alternatives. W...