aflatoxins are carcinogenic metabolites produced by several strains of aspergillus flavus group in food and feed. cluster genes in aflatoxin biosynthesis pathway contain structural, regular and unassigned genes , nor-1 , ver-1 , and omt-1 are structural genes that coding for key enzymes and aflr is a regulatory gene that plays a key role in the production of aflatoxin and is affecting on the st...

background aflatoxins are highly toxic secondary metabolites mainly produced by aspergillus parasiticus. this species can contaminate a wide range of agricultural commodities, including cereals, peanuts, and crops in the field. in recent years, research on medicinal herbs, such as pistacia atlantica subsp. kurdica, have led to reduced microbial growth, and these herbs also have a particular eff...

Background and Purpose: Mycotoxins are secondary fungal metabolites with a very high diversity that are produced by some species of Aspergillus which frequently leads to contaminate food and agricultural products. Recently, elimination of aflatoxin contamination in food and feed has been considered by scientists worldwide. Although, the antibacterial and antifungal effects of vitamins as natura...

PksA catalyzes the formation of the polyketide backbone necessary for aflatoxin biosynthesis. Based on reporter assays and sequence comparisons of the nor1-pksA intergenic region in different aflatoxin-producing Aspergillus species, cis-acting elements for the aflatoxin pathway-specific regulatory protein, AflR, and the global-acting regulatory proteins BrlA and PacC are involved in pksA promot...

1Key Laboratory of Pathogenic Fungi and Mycotoxins of Fujian Province, Fujian Agriculture and Forestry University, China 2Key Laboratory of Biopesticide and Chemical Biology of Education Ministry, and School of Life Science, Fujian Agriculture and Forestry University, China 3Key Laboratory of Agroecological Processing and Safety Monitoring, Fujian Agriculture and Forestry University, China 4Ins...

Secondary metabolism is commonly associated with morphological development in microorganisms, including fungi. We found that veA, a gene previously shown to control the Aspergillus nidulans sexual/asexual developmental ratio in response to light, also controls secondary metabolism. Specifically, veA regulates the expression of genes implicated in the synthesis of the mycotoxin sterigmatocystin ...

BACKGROUND AND PURPOSE Mycotoxins are secondary fungal metabolites with a very high diversity that are produced by some species of Aspergillus which frequently leads to contaminate food and agricultural products. Recently, elimination of aflatoxin contamination in food and feed has been considered by scientists worldwide. Although, the antibacterial and antifungal effects of vitamins as natural...

A total of 112 fungal isolates were recovered from cereal grains collected from 10 districts of Tamilnadu and Andhra Pradesh states. The collected samples were subjected to standard blotter method and different ochratoxigenic Aspergillus and Penicillium species were isolated and maintained. A multiplex PCR assay was standardized for simultaneous detection of toxigenic Aspergillus and ochratoxin...