OBJECTIVE To evaluate the temporal evolution and diagnostic values of the diffusion tensor imaging (DTI) and the high b value diffusion weighted imaging (DWI) in the early permanent and transient cerebral ischemia. MATERIALS AND METHODS For permanent or 30-minute transient-ischemia induced 30 rats, DTI and DWIs at both high b (b = 3000 s/mm(2)) and standard b value (b = 1000 s/mm(2)) were obt...

PURPOSE To study the correlation between apparent diffusion coefficient (ADC) and pathology in patients with undefined breast lesion, to validate how accurately ADC is related to histology, and to define a threshold value of ADC to distinguish malignant from benign lesions. MATERIALS AND METHODS Seventy-eight patients (110 lesions) were referred for positive or dubious findings. Three-dimensi...

BACKGROUND AND PURPOSE Identifying tissue at risk for infarction is an important goal of stroke imaging. This study was performed to determine whether pixel-based apparent diffusion coefficient (ADC) and signal intensity ratio are helpful diffusion-weighted (DW) imaging metrics to predict tissue at risk for infarction. METHODS Twelve patients presenting with acute hemispheric strokes underwen...

Introduction Cerebral edema (CE) is the key factor for the development of secondary brain injuries after severe traumatic brain injury (TBI). This edema may be assessed using the averaged Apparent diffusion coefficient (ADC) measured by diffusion-weighted MRI in specified ROI. However, this approach does not take into account the complexity and the heterogeneity of the post traumatic edema. The...

BACKGROUND AND PURPOSE Recent studies have shown that the brain ischemic area defined by the map of decreased apparent diffusion coefficient (ADC) obtained by diffusion-weighted imaging (DWI) during the first hours of ischemic stroke includes a significant part of ischemic penumbra. We hypothesize that the misjudgment of the final infarct size by ADC mapping may be related to a restricted abili...

Introduction: Diffusion weighted imaging is a powerful tool for the diagnosis of prostate cancer. In radiotherapy, delineation of the tumor for dose escalation is an important issue. Therefore, clear tumor boundaries have to be distinguished. In tumors, the diffusion direction of water is thought to be isotropic. The fractional anisotropy in the peripheral zone and central zone is reported to b...

BACKGROUND AND AIM To assess the role of diffusion weighted imaging sequence (DWI), routinely used in hepatic magnetic resonance imaging (MRI) for the differentiation of hepatocellular carcinoma (HCC) from benign liver lesions. METHODS A number of 56 liver MRI examinations were retrospectively analyzed independently by two experienced radiologists, blinded to each other results. A total numbe...

PURPOSE To map the gene for autosomal dominant cataracts (ADC) in an American white family of European descent. METHODS Ophthalmic examinations and linkage analyses using a variety of polymorphisms were performed; two-point lod scores calculated. RESULTS Affected individuals (14 studied) exhibited variable expressivity of embryonal nuclear opacities based on morphology, location within the ...

Abstract Background Papilledema is optic disc pathology characterized by swelling of the occurring secondary to elevated intracranial pressure (ICP), and it was proposed that ICP transferred along subarachnoid space nerve (ON) leading metabolic process interruptions MRI changes within ON head. This study aimed rule out if DWI ADC map can be used as a diagnostic tool for detection papilledema va...