A natural extension of the trend of increased involvement in science is the concept of a Robot Scientist [King et al. (2004),King et al. (2009)]. A Robot Scientist automatically: originates hypotheses to explain observations, devises experiments to test these hypotheses, physically runs the experiments using laboratory robotics, interprets the results to change the probability of hypotheses, an...

......................................................................................................................... 2 Trust: Economic Notions and its role in Money and Banking – An Introduction ....... 11 Realism .................................................................................................................... 12 Open Systems and Closed systems .............................

The presence of moral evil (sin) in the world is relatively easy for the Christian creationist to explain, and free choice is key to that explanation. To Christian evolutionist and professor of biology Daniel Brannan, the idea of a very good Creation and an Adam and Eve who were deceived and sinned is not only incoherent but also makes God the cause of sin. Brannan proposed that Christians acce...

REGULATION OF NUCLEAR LAMIN POLYMERIZATION BY IMPORTIN  Adam, Stephen A., Kaushik Sengupta, and Robert D. Goldman From Department of Cell and Molecular Biology Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611 1 These authors contributed equally to this work. Address correspondence to Stephen A. Adam, Ph.D., W129 303 E. Chicago Avenue, Chicago IL 60611 Fax: 312-503-7...

The ADAMs are a family of membrane proteins possessing a disintegrin and metalloprotease domain. One of their main functions is shedding of membrane proteins. The aim of this study was to test the hypothesis that ADAM-17 (also known as tumor necrosis factor-alpha converting enzyme) is involved in breast cancer progression. Overexpression of ADAM-17 in MCF-7 breast cancer cells increased in vitr...

BACKGROUND Cranial neural-crest (CNC) cells originate from the lateral edge of the anterior neuroepithelium and migrate to form parts of the peripheral nervous system, muscles, cartilage, and bones of the face. Neural crest-cell migration involves the loss of adhesion from the surrounding neuroepithelium and a corresponding increase in cell adhesion to the extracellular matrix (ECM) present in ...

There are two competing approaches sustainability in agriculture. One stresses a strict economic approach in which market forces should be allowed to guide the activities of agricultural producers. The other advocates the need to balance economic with environmental and social objectives, even to the point of reducing profitability. This paper shows how the writings of the 18 century moral philo...

BACKGROUND Our study is to research the effect of inhibited ADAM-17 expression through the Notch pathway in renal carcinoma. METHODS Immunohistochemistry and western blot were used to examine the expression of ADAM-17 protein in renal cancer tissues. Proliferation and cell invasion of 786-o cells, as well as OS-RC-2 cells, after treatment with two different inhibitors of the Notch pathway, we...

Optimization algorithms for training deep models not only affects the convergence rate and stability of the training process, but are also highly related to the generalization performance of the models. While adaptive algorithms, such as Adam and RMSprop, have shown better optimization performance than stochastic gradient descent (SGD) in many scenarios, they often lead to worse generalization ...