Glycoprotein (GP) IIb/IIIa inhibitors have been extensively studied in the setting of percutaneous coronary intervention (PCI) and in the management of non-ST-segment elevation acute coronary syndromes. However, the use of GP IIb/IIIa inhibitors is less well established in the setting of acute ST-segment elevation myocardial infarction (MI). Multiple nonrandomized studies suggest that combinati...

OBJECTIVE In acute coronary syndromes, switching between thienopyridines is frequent. The aims of the study were to assess the association between switching practices and quality of care. METHODS Registry study performed in 213 French public university, public non-academic and private hospitals. All consecutive patients admitted for acute myocardial infarction (MI; <48 hours) between 1/10/201...

OBJECTIVES We sought to evaluate the utility of excluding myocardial infarction (MI) in patients presenting to the emergency department (ED) with atrial fibrillation (AF) and to identify predictors of MI in this group. BACKGROUND Patients with AF are frequently admitted to the hospital, in part, to exclude an associated MI. There are no prospective data on unselected patients to support this ...

Blood pressure is 115/78 mm Hg; heart rate, 65 beats per minute; and respiration rate, 30 breaths per minute. Neck veins are markedly distended; lung fields are clear. A 12-lead ECG (A) shows sinus rhythm with ST-segment elevation in leads II, III, and aVF; ST-segment depression is evident in leads I and aVL. These ECG findings are interpreted as acute inferior wall myocardial infarction (MI) w...

BACKGROUND The purpose of this observational study was to test the diagnostic performance of the Elecsys® troponin T high-sensitive system combined with copeptin measurement for early exclusion of acute myocardial infarction (MI) in clinical practice. METHODS Troponin T high-sensitive (diagnostic cutoff: <14 pg/mL) and copeptin (diagnostic cutoff: <14 pmol/L) levels were determined at admissi...

BACKGROUND Acute myocardial infarction (MI) following anaphylaxis is rare, especially in subjects with normal coronary arteries. The exact pathogenetic mechanism of MI in anaphylaxis remains unclear. CASE PRESENTATION The case of a 32-year-old asthmatic male with systemic anaphylaxis, due to oral intake of 500 mg amoxycillin, complicated by acute ST-elevation MI is the subject of this report....

Although acute pericarditis has charachteristic electrocardiographic (ECG) findings that differentiate it from acute ST segment elevation myocardial infarction (MI); in certain cases diagnosis is somewhat difficult especially when the ECG reveals focal instead of diffuse changes and moreover when pericarditis is associated with an underlying myocarditis causing elevation of the cardiac biomarke...

egory of coronary heart disease that ranges from unstable angina to ST elevation myocardial infarction (MI). Its initial evaluation relies heavily on rapid triage according to the electrocardiogram and cardiac biomarkers. The cornerstone of treatment for ST ele vation MI is rapid reperfusion, which can be achieved either by fibrinolysis or primary percutaneous coronary intervention (PCI). When ...

in patients with acute coronary syndromes: a collaborative meta-analysis of randomized trials. JAMA 2005;293:2908–2917. 5. Antman EM, Cohen M, Bernink PJ, McCabe CH, Horacek T, Papuchis G, Mautner B, Corbalan R, Radley D, Braunwald E. The TIMI risk score for unstable angina/non-ST-elevation MI: a method for prognostication and therapeutic decision making. JAMA 2000;284:835–842. 6. Yan AT, Yan R...