Severe sepsis is a major concern in the intensive care unit (ICU), although there is very little epidemiological information regarding severe sepsis in Japan. This study evaluated 3195 patients with severe sepsis in 42 ICUs throughout Japan. The patients with severe sepsis had a mean age of 70 ± 15 years and a mean Acute Physiology and Chronic Health Evaluation II score of 23 ± 9. The estimated...

INTRODUCTION Systemic lupus erythematosus (SLE) is an archetypal autoimmune disease, involving multiple organ systems with varying course and prognosis. However, there is a paucity of clinical data regarding prognostic factors in SLE patients admitted to the intensive care unit (ICU). METHODS From January 1992 to December 2000, all patients admitted to the ICU with a diagnosis of SLE were inc...

OBJECTIVE To identify the independent variables associated with death within 4 days after the first sepsis-induced organ dysfunction. METHODS In this prospective observational study, severe sepsis and septic shock patients were classified into 3 groups: Group 1, survivors; Group 2, late non-survivors; and Group 3, early non-survivors. Early death was defined as death occurring within 4 days a...

Background Perforation is the second most frequent complication of colonic cancer (c.c.). It represents 0.8%–3.7% of all c.c. surgically treated and 10%–26% of those operated on in emergency. The resection rate of c.c. perforations is increased in the last decade reaching 95% or more. Hinchey classification, Mannheim Peritonitis Index (M.P.I.) (5) and Acute Physiology and Chronic Health Evaluat...

This study was designed to assess whether plasma cy-tokines correlated with the clinical status of postsurgical patients. Plasma levels of cytokines in 72 patients admitted to the intensive care unit were measured using an Enzyme Linked Immuno Solubent Assay. The clinical status was evaluated with the Acute Physiology Age and Chronic Health Evaluation (APACHE) 11 scoring system. There were sign...

To explore the following hypotheses: 1) Gas exchange, Organ failure, Cause, Associated disease (GOCA) score, which reflects both general health and the severity of lung injury, would be a better mortality predictor of acute respiratory distress syndrome (ARDS) than acute physiology and chronic health evaluation (APACHE II) or simplified acute physiology score (SAPS II), which are not specific t...

OBJECTIVE This study aimed to describe and compare the characteristics and clinical outcomes of patients with septic and non-septic acute kidney injury. METHODS This study evaluated an open cohort of 117 critically ill patients with acute kidney injury who were consecutively admitted to an intensive care unit, excluding patients with a history of advanced-stage chronic kidney disease, kidney ...

Abstract. To date, numerous studies continue to identify factors that significantly affect the outcome of treatment intraperitoneal infections.
 The proposed work: improve existing systems for assessing severity patient’s condition by modification aimed at adapting capabilities most domestic clinics.
 Material and methods. Based on analysis clinical laboratory data obtained in 183 pat...