A simple, 30-mm method of estimating the binding of bilirubin to serum protein was compared with a quantitative method. Good correlation was found between the two methods, both based on Sephadex gel filtration. The results indicate that the presence of loosely bound bilirubin can be determined with this simple, qualitative, semimicro-scale test. This determination is important for the clinical ...

BACKGROUND Neonatal jaundice (NNJ) is common, but few root cause analyses based on national quality registries have been performed. An online registry was established to estimate the incidence of NNJ in Turkey and to facilitate a root cause analysis of NNJ and its complications. METHODS A multicenter prospective study was conducted on otherwise healthy newborns born at ≥35 weeks of gestation ...

Despite efforts to eliminate permanent and irreversible brain damage due to bilirubin encephalopathy and kernicterus, these conditions continue to accompany us into the third millennium. This phenomenon occurs not only in developing countries with emerging medical systems, but in Westernized countries as well. Comprehensive guidelines to detect newborns with jaundice and treat those in whom hyp...

INTRODUCTION Considering the prevalence of Jaundice in newborn infants and the risk of developing acute Bilirubin encephalopathy, in early weeks after birth. the importance of Infancy, as well as positive effects of giving massage on physical and behavioral growth and evolution of infants, the current study has been aimed to investigate the effects of Vimala massage on neonatal physiological Ja...

An enzymatic assay is described for non-albuminbound bilirubin in the serum of newborn infants. Unbound bilirubin is oxidized to colorless compounds by ethyl hydroperoxide in the presence of horseradish peroxidase (EC 1.11.1.7), while albumin-bound bilirubin is protected from oxidation. Because the equilibrium between albumin and bilirubin occurs rapidly, the oxidation step is rate limiting, an...

Radiol Bras. 2016 Nov/Dez;49(6):406–413 408 http://dx.doi.org/10.1590/0100-3984.2015.0190 There is a broad spectrum of diagnoses of bilateral lesions in the basal ganglia in the pediatric population. The main causes cited are hypoxic-ischemic encephalopathy; hypoglycemia; encephalitis; inborn errors of metabolism; water and electrolyte disturbances; carbon monoxide poisoning; and demyelinating ...

impression that kernicterus has virtually " become extinct " with the near elimination of Rh disease is incorrect. In fact, this neurological condition is experiencing a re-emergence, likely due to earlier hospital discharge and a " more lax " approach to the treatment of neonatal hyperbilirubinemia. 1 Up to one in 700 healthy term newborns may be at risk of kernicterus due to severe hyperbilir...