Cystic Fibrosis (CF) is a frequent and lethal autosomal recessive disease, caused by mutations in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR). Before the discovery of the CFTR gene, several hypotheses attempted to explain the etiology of this disease, including the possible role of a chloride channel, diverse alterations in mitochondrial functions, the overe...

Previous research demonstrated a relationship between the temporal pattern of heterosexual activity and an index of ovarian functioning. In the current study, this relationship was investigated in 147 menstruating heterosexual women (aged 19-53). They kept prospective daily records of menses, basal body temperature, sexual activity, and other behaviors for three consecutive menstrual cycles. In...

The increasing recognition of non-arteriosclerotic endomyocardial fibrosis as a significant cause of congestive cardiac failure in adults outside Africa as well as in Africa is noted. Five new cases occurring in Great Britain (one in an African) are added to the mounting literature on the subject. The main clinical and pathological features are summarized, and the suggestion is made that early ...

We develop a bicriteria model for the resource allocation problem in PERT networks, in which the total direct costs of the project as the first objective, and the mean of project completion time as the second objective are minimized. The activity durations are assumed to be independent random variables with either exponential or Erlang distributions, in which the mean of each activity duration ...

vitamin d3 has a role in many autoimmune diseases and appears to play a function in controlling rheumatoid arthritis (ra). the aim of this study is to evaluate the relationship between serum level of vitamin d and ra disease activity score. the serum level of vitamin d in 75 ra patients referred to the rheumatology clinic of rasoul-akram hospital was measured. patients were classified into low,...

the toxicity of chlorpyrifos to three iranian populations of two-spotted spider mite, collected from isfahan (isr), yazd (yz) and guilan (gus2) provinces were surveyed using the residual contact vial bioassay. the bioassay results showed that resistance ratios of isr and yz populations were 176.90 and 9.78 fold compared to the gus2 population, respectively. determination of esterase and glutath...

malting is a complex biotechnological process that includes steeping; germination and drying of cereal grains under controlled conditions of temperature and humidity. in this research malting process parameters were predict by modular neural network with different activation function included, logsig-logsig, tanh-tanh, logsigtanh, logsig-identity and tanh-identity. steeping time (x1) and germin...

we present a 55-year old male patient who was subjected to whole body skeletal scintigraphy for metastatic work up of urinary bladder cancer. whole body 99mtc-methylene diphosphonate (mdp) skeletal scintigraphy was performed. that revealed no skeletal metastasis in the entire body skeleton and normally visualized left kidney with empty right renal fossa. additionally tracer activity collected i...

Background & Aims: Precise muscle activity pattern is required to maintain normal shoulder function and any alteration in muscle activity can result in movement impairment. The purpose of this study was to assess normalized electromyography (EMG) of shoulder muscles during selected functional tasks of upper limb in patients with shoulder impingement syndrome. Methods: Test group consisted of 15...