BACKGROUND A fistula between the duodenum and the main portal vein near a peptic ulcer is extremely rare, and only two cases of duodenal ulcers have been reported in the past. CASE PRESENTATION We report a 68-year-old man with a diagnosis of anemia who had a history of extended right hepatectomy for hilar cholangiocarcinoma 20 months previously. The first endoscopic examination revealed a gia...

Humans can be incidentally parasitized by third-stage larvae of Anisakis species following the ingestion of raw or undercooked seafood. Acute gastric anisakiasis is one of the most frequently encountered complaints in Korea. However, duodenal anisakiasis with duodenal ulcer had not been reported in Korea, despite the habit of eating raw fish. In this case, a 47-year-old man was hospitalized bec...

A 51-year-old white man presented to the emergency department with a 3-month history of atypical chest pain, odynophagia to solids and liquids, and a 18-kg weight loss. He was febrile to 39oC and tachycardic. Physical exam was remarkable for bilateral submandibular lymphadenopathy and thrush in the posterior oropharynx. He was diagnosed with AIDS with CD4 count 146 cells/mm3 and viral load 423,...

Telomerase is the enzyme that maintains telomere length by adding telomeric repeats after each cell division. Numerous metabolic factors such as obesity, insulin resistance or physical inactivity have been associated with shortened telomeres. In the present study, we assessed telomerase activity in diabetic patients having or not foot ulcer. A total of 90 adult patients with type 2 diabetes mel...

BACKGROUND Studies that report prevention of ulcer recurrence among long-term users of nonsteroidal anti-inflammatory drugs (NSAIDs) that do not stratify for Helicobacter pylori status may not be generalizable to the large population of individuals without H pylori. METHODS This was a prospective, double-blind, multicenter, active- and placebo-controlled study among 537 patients without H pyl...

Abnormalities of duodenal motility have been described in patients with duodenal ulcer and in experimental ulcers in rats and it has been postulated that they could be pathogenic in peptic ulcer disease. We have investigated with an isotopic technique whether duodenal bulb clearance or duodenal transit are abnormal in duodenal ulcer. Six patients with inactive and six with active duodenal ulcer...

Introduction: Fuligo Plantae (FP), the ash that sticks to bottom of pots or chimneys after weeds burn, has long been used for its hemostatic effects and treatment gastrointestinal bleeding. Nevertheless, active ingredient FP still needs be further explored. Methods: The microstructure, optical chemical properties FP-CDs were characterized. An alcohol-induced gastric ulcer model was utilized eva...

Epidemiological studies using serological tests have shown that a large proportion of healthy people have antibodies against Helicobacter pylori (anti-Hp). It is uncertain whether the presence of anti-Hp indicates active infection or only past exposure to the micro-organism. In this study we determined anti-Hp with a specific enzyme linked immunosorbent assay in 100 healthy volunteers who were ...

Quality of ulcer healing (QOUH) is defined as ideal ulcer healing featuring with the fine granular ulcer scar, high functional restoration and the resistance to recurrence. This study was designed to compare the rates of QOUH achievement in rat gastric ulcer model between acid suppressant treated group and gastroprotectant treated group accompanied with elucidations of molecular mechanisms. Ser...

the antiulcer effects of different tricyclic antidepressants (trimipramine, doxepin, imipramine, and amitriptyline) in comparison with those of cimetidine, pirenzepine and omeprazole were investigated in male rats with acute gastric ulcer. acute gastric ulcer was induced by oral administration of o. 6n hcl solution, 1 ml/rat. pretreatment of animals with doxepin, trimipramine, amitriptyline, im...