We analyzed phenolic compounds in the leaves of Pedicularis chamissonis which were obtained from a wide range of Japan. Acteoside and luteolin 7-O-glucuronide were found as major compounds in the all plants from various populations. Luteolin 7-O-glucoside was additionally found in the plants sampled from in the southern part of their habitats. Fujii et al. (2013) divided the plants into two spe...

A new phenylethanoid tetraglycoside, physocalycoside (2), was isolated from the aerial parts of Phlomis physocalyx. Its structure was identified as 3-hydroxy-4-methoxy-beta-phenylethoxy-O-[alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-rhamnopyranosyl-(1-->3)]-4-O-feruloyl-[beta-D-glucopyranosyl-(1-->6)]-beta-D-glucopyranoside, on the basis of spectroscopic evidence. In addition, one known iridoid glu...

From the leaves and branches Barnettia kerrii, two verbascoside derivatives (6"-O-acetylverbascoside and 4"'-O-acetylverbascoside), as well as two phenolic glycosides (khaephuosides A and B) were isolated together with 15 known compounds. The structural elucidations were based on analyses of spectroscopic data.

Two phenylethanoid glycosides, acteoside and forsythoside B, were first isolated from the traditional Chinese herb Callicarpa peii H.T. Chang. The interaction between the two phenylethanoid glycosides and bovine serum albumin (BSA) was investigated by fluorescence, UV-vis absorbance and circular dichroism (CD). The results showed that the quenching mechanism in the drug-BSA binary systems was a...

Cancer is a set of diseases including abnormal growth cells that can spread to another tissue. Verbascoside (or acteoside) naturally occurring, water-soluble secondary metabolite with significant biological properties, which distributed widely in plant kingdom. pharmacologically active compounds many recent evidences support its activities and safety. This review focuses on the studies concerne...

Abstract Background Chinese materia medica processing is a distinguished and unique pharmaceutical technique in Traditional Medicine (TCM) used for reducing side effects, increasing or even changing therapeutic efficacy of the raw herbs.Changes essential components induced by an optimized procedure are primarily responsible increased medicinal plants.The kidney-yang invigorating effect rice win...

Sortase A (SrtA) has long been recognized as an ideal drug target for therapeutic agents against Gram-positive pathogens. However, the SrtA of Streptococcus suis (Ss-SrtA), an important zoonotic agent, has not been studied. In this study, the enzymatic properties of Ss-SrtA were investigated, and inhibition of Ss-SrtA by natural products was evaluated. Ss-SrtA was expressed and purified. The pu...