In the crystal structure of the title compound, C(21)H(18)N(+)·CF(3)OS(3) (-), the cations form inversion dimers through π-π inter-actions between the acridine ring systems. These dimers are further linked by C-H⋯π inter-actions. The cations and anions are connected by C-H⋯O, C-F⋯π and S-O⋯π inter-actions. The acridine and benzene ring systems are oriented at a dihedral angle of 76.8 (1)°with r...

In the crystal structure of the title compound, C(23)H(20)NO(2) (+)·CF(3)SO(3) (-), adjacent cations are linked through a network of C-H⋯π and π-π inter-actions, and neighboring cations and anions via C-H⋯O inter-actions. The acridine and benzene ring systems are oriented at a dihedral angle of 31.4 (1)°. The carboxyl group is twisted at an angle of 66.3 (1)° relative to the acridine skeleton. ...

In the crystal of the title compound, C(24)H(22)NO(2) (+)·CF(3)SO(3) (-), adjacent cations and anions are connected through C-H⋯O, C-H⋯F and S-O⋯π inter-actions, while neighboring cations via π-π inter-actions [centroid-centroid distance = 3.962 (2) Å]. The acridine and benzene ring systems are oriented at a dihedral angle of 14.6 (1)°. The carboxyl group is twisted at an angle of 87.6 (1)° rel...

In the crystal of the title compound, C(21)H(15)ClNO(2) (+)·CF(3)SO(3) (-), adjacent cations are linked through C-H⋯π and π-π inter-actions [centroid-centroid distance = 3.987 (2) Å], and neighboring cations and anions via C-H⋯O and C-F⋯π inter-actions. The acridine ring system and benzene ring are oriented at a dihedral angle of 1.0 (1)° while the carboxyl group is twisted at an angle of 85.0 ...

The use of digitonin to permeabilize the plasma membrane of Trypanosoma brucei procyclic and bloodstream trypomastigotes allowed the identification of a non-mitochondrial nigericin-sensitive Ca2+ compartment. The proton ionophore carbonyl cyanide p-trifluoromethoxyphenylhydrazone (FCCP) was able to cause Ca2+ release from this compartment, which was also sensitive to sodium orthovanadate. Prein...

Rapid diagnosis is a prerequisite for institution of effective treatment and reducing the mortality and morbidity of falciparum malaria. This study was taken up to compare the efficacy of various rapid methods viz, acridine orange, Plasmodium falciparum histidine rich protein II antigen detection and Field's stain with traditional microscopy i.e, Leishman stain for diagnosing falciparum malaria...

An acridine derivative was covalently linked to the 5' end of a homopyrimidine oligonucleotide. Specific binding to a homopurine-homopyrimidine sequence of duplex DNA was demonstrated by spectroscopic studies (absorption and fluorescence) and by "footprinting" experiments with a copper phenanthroline chelate used as an artificial nuclease. A hypochromism and a red shift of the acridine absorpti...