OBJECTIVE To evaluate variations in laboratory parameters and diagnoses of selected clinical conditions up to 16 weeks after starting a new systemic psoriasis treatment for Psocare Registry enrollees. DESIGN Prospective cohort study. SETTING Italian public referral centres for psoriasis treatment. PATIENTS First-time recipients (n = 10,539) of continuous systemic psoriasis treatment for a...

PURPOSE Besides being widely used in cosmetics, retinoids are potent therapeutic agents used topically and systemically as anti-acne agents. The aim of this study was to predict with the use of MetaSite the skin metabolism of selected retinoids employed in treatment of skin disorders and found in cosmeceuticals. The following compounds were studied: retinol, retinaldehyde, retinoic acid, retiny...

Background: Psoriasis treatment is very important regard to mental sequeler and creating morbidity. First line treatment of generalized plaque type psoriasis includes methotrexate, phototherapy and retinoids. Objective: To compare bath-PUVA and acitretin in the treatment of generalized plaque type psoriasis. Patients and Methods: 40 patients with generalized plaque type psoriasis with PAS...

In this case report, we present a 30-year-old man who developed pityriasis rubra pilaris (PRP) following exposure to Dolomite. The diagnosis of PRP was confirmed histologically and the patient was successfully treated with acitretin and cyclosporine.