1. The isolated perfused kidneys of fed rats in normal acid-base status showed a constant rate of lactate removal from the perfusate between 5 and 90 min of perfusion at a perfusate pH of 7-4-7-5. 2. Lactate removal by kidneys of rats in normal acid-base status was stimulated within 30 min by a reduction in perfusate pH to 7-1-7-2, but depressed when perfusate pH was reduced further. 3. Kidneys...

The discovery in the late 1960s of ‘dead’ or dying lakes (Beamish and Harvey, 1972) nearly devoid of living animals and plants owing to the effects of acid precipitation spawned intense research into the effects of low pH environments on the physiology of freshwater fish. Over the next decade, an extensive body of literature documented the adverse effects of acid environments on acid–base statu...

OBJECTIVE To study acid-base status during a constant-load treadmill test at exercise levels close to the maximum lactate steady-state. DESIGN Two tests were performed: one maximal and one steady-state at a load corresponding to the mean of the two ventilatory thresholds observed in the first test. SETTING University Sports Science Laboratory. PARTICIPANTS Twenty-three male Sports Science...

Carbonic anhydrase (CA) is the zinc metalloenzyme that catalyses the reversible reactions of CO(2) with water. CA plays a crucial role in systemic acid-base regulation in fish by providing acid-base equivalents for exchange with the environment. Unlike air-breathing vertebrates, which frequently utilize alterations of breathing (respiratory compensation) to regulate acid-base status, acid-base ...

in this study, bis(salicylaldehyde)-4-methyl-1,2-phenylenediimine (bsmp) as a schiff base ligand of n2o2-type and its mn and fe complex as m-bsmp catalyst were synthesized and characterized by uv-vis, ir spectroscopy and elemental analysis. the efficiency of fe- and mn-bsmp catalysts was evaluated in the oxidative decarboxylation of arylacetic acids with tetra-butylammonium periodate (n-bu4nio4...

To study the extracellular acid-base equilibrium in vivo, it is necessary to obtain arterial blood samples without inducing concomitant respiratory or metabolic disturbances. Respiratory artifacts have been reported when general anesthesia had to be induced to allow the tapping of blood [1—5]. Similarly, blood collected by heart puncture or fast decapitation may not accurately reflect the acid-...

Metabolic acidosis is a common finding after cardiac arrest. Until recently this acidosis was mainly attributed to lactate. The physico-chemical approach to acid-base balance permits the detection of previously unmeasured ions. These ions have been shown to affect the acid-base status of patients.